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1.5.1.22: Strombine dehydrogenase

This is an abbreviated version!
For detailed information about Strombine dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.22

Reaction

N-(carboxymethyl)-D-alanine
+
NAD+
+
H2O
=
glycine
+
pyruvate
+
NADH
+
H+

Synonyms

Dehydrogenase, strombine, SDH, St/AlDH1, St/AlDH2, St/AlDH3, StDH, STRDH, strombine dehydrogenase, strombine/alanopine dehydrogenase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.22 Strombine dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.5.1.22 - Strombine dehydrogenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
glycine + pyruvate + NADH + H+
N-(carboxymethyl)-D-alanine + NAD+ + H2O
show the reaction diagram
-
the reduction reaction is preferred
-
-
r
additional information
?
-
-
the enzyme functions as the terminal dehydrogenase of glycolysis and has a role in maintaining energy production under the stresses of environmental or functional anoxia
-
-
?