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1.5.1.25: thiomorpholine-carboxylate dehydrogenase

This is an abbreviated version!
For detailed information about thiomorpholine-carboxylate dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.25

Reaction

Thiomorpholine 3-carboxylate
+
NAD(P)+
=
3,4-dehydro-thiomorpholine-3-carboxylate
 +
NAD(P)H
 +
H+

Synonyms

CRYM, CtBP, cytosolic thyroid hormone binding protein, DELTA1-piperideine-2-carboxylate reductase, ketimine reductase, ketimine-reducing enzyme, KR/CRYM/CTBP, More, mu-crystallin, P2C reductase, PLP-dependent amino acid gamma-substitution enzyme, PYCR2, Pyr2C reductase, reductase, ketimine, THBP, thyroid hormone binding protein, Thyroid hormone-binding protein

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.25 thiomorpholine-carboxylate dehydrogenase

Subunits

Subunits on EC 1.5.1.25 - thiomorpholine-carboxylate dehydrogenase

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SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
dimer
-
2 * 45000, SDS-PAGE
homodimer
additional information
each subunit contains two distinct domains linked by an alpha-helix. The first domain (a dinucleotide binding domain) binds NADPH or NADP+ and is built around a Rossmann fold-like motif. The second domain is the dimerization domain and is responsible for recognition and binding of thyroid hormones