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1.5.1.40: 8-hydroxy-5-deazaflavin:NADPH oxidoreductase

This is an abbreviated version!
For detailed information about 8-hydroxy-5-deazaflavin:NADPH oxidoreductase, go to the full flat file.

Word Map on EC 1.5.1.40

Reaction

reduced coenzyme F420
+
NADP+
=
oxidized coenzyme F420
 +
NADPH
 +
H+

Synonyms

5-deazaflavin-NADP+ reductase, 8-hydroxy-5-deazaflavin-dependent NADP+ reductase, 8-OH-5-deazaflavin:NADPH oxidoreductase, 8-OH-5dFl:NADPH oxidoreductase, AF0892, F420-dependent NADP oxidoreductase, F420-dependent NADP reductase, F420-dependent NADP+ oxidoreductase, F420:NADPH oxidoreductase, F420H2:NADP oxidoreductase, F420H2:NADP+ oxidoreductase, Fno, Msm_0049, NADP+:F420 oxidoreductase, Tfu-FNO, Tfu_0970

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase

pH Range

pH Range on EC 1.5.1.40 - 8-hydroxy-5-deazaflavin:NADPH oxidoreductase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4.3 - 6.7
-
pH 4.3: about 50% of maximal activity, pH 6.7: about 50% of maximal activity
4.5 - 6.5
pH 4.5: about 45% of maximal activity, pH 6.5: about 35% of maximal activity, reduction of oxidized coenzyme F420 with NADPH
7 - 9
pH 7.0: about 60% of maximal activity, pH 9.0: about 50% of maximal activity, reduction of NADP+ with reduced coenzyme F420
7.5 - 10
pH 7.5: about 50% of maximal activity, pH 10.0: about 90% of maximal activity, reduction of NADP+ with reduced coenzyme F420