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1.5.1.44: festuclavine dehydrogenase

This is an abbreviated version!
For detailed information about festuclavine dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.44

Reaction

festuclavine
+
NAD+
=
6,8-dimethyl-6,7-didehydroergoline
+
NADH
+
H+

Synonyms

EasA, EasG, ergot alkaloid biosynthetic protein G, festuclavine synthase, festuclavine synthase I, festuclavine synthase II, FgaFS, ifgF1, ifgF2, isofumigaclavine biosynthesis cluster A protein F1, isofumigaclavine biosynthesis cluster A protein F2

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.44 festuclavine dehydrogenase

Reference

Reference on EC 1.5.1.44 - festuclavine dehydrogenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cheng, J.; Coyle, C.; Panaccione, D.; OConnor, S.
Controlling a structural branch point in ergot alkaloid biosynthesis
J. Am. Chem. Soc.
132
12835-12837
2010
Aspergillus fumigatus
Manually annotated by BRENDA team
Xie, X.; Wallwey, C.; Matuschek, M.; Steinbach, K.; Li, S.M.
Formyl migration product of chanoclavine-I aldehyde in the presence of the old yellow enzyme FgaOx3 from Aspergillus fumigatus: a NMR structure elucidation
Magn. Reson. Chem.
49
678-681
2011
Aspergillus fumigatus
Manually annotated by BRENDA team
Wallwey, C.; Matuschek, M.; Xie, X.; Li, S.
Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3
Org. Biomol. Chem.
8
3500-3508
2010
Aspergillus fumigatus, Aspergillus fumigatus Af293
Manually annotated by BRENDA team
Matuschek, M.; Wallwey, C.; Xie, X.; Li, S.M.
New insights into ergot alkaloid biosynthesis in Claviceps purpurea: an agroclavine synthase EasG catalyses, via a non-enzymatic adduct with reduced glutathione, the conversion of chanoclavine-I aldehyde to agroclavine
Org. Biomol. Chem.
9
4328-4335
2011
Aspergillus fumigatus
Manually annotated by BRENDA team
Matuschek, M.; Wallwey, C.; Wollinsky, B.; Xie, X.; Li, S.
In vitro conversion of chanoclavine-I aldehyde to the stereoisomers festuclavine and pyroclavine controlled by the second reduction step
RSC Adv.
2
3662-3669
2012
Aspergillus fumigatus, Claviceps purpurea, Penicillium commune (I6U936), Aspergillus fumigatus Af293, Penicillium commune NRRL2033 (I6U936)
-
Manually annotated by BRENDA team
Gerhards, N.; Li, S.M.
A bifunctional old yellow enzyme from Penicillium roqueforti is involved in ergot alkaloid biosynthesis
Org. Biomol. Chem.
15
8059-8071
2017
Penicillium camemberti, Penicillium commune (I6U936), Penicillium roqueforti (W6QRI9), Penicillium roqueforti, Penicillium roqueforti FM164 (W6QRI9), Penicillium camemberti DSM 1233
Manually annotated by BRENDA team
Martin, J.F.; Alvarez-Alvarez, R.; Liras, P.
Clavine alkaloids gene clusters of Penicillium and related fungi evolutionary combination of prenyltransferases, monooxygenases and dioxygenases
Genes (Basel)
8
342
2017
Penicillium camemberti, Penicillium griseofulvum, Penicillium expansum (A0A0A2J928), Penicillium steckii (A0A1V6SJK0), Penicillium commune (I6U936), Aspergillus fumigatus (Q4WZ69), Penicillium roqueforti (W6Q1E9), Penicillium roqueforti (W6QRI9), Penicillium roqueforti FM164 (W6Q1E9), Penicillium roqueforti FM164 (W6QRI9), Aspergillus fumigatus CBS 101355 (Q4WZ69), Aspergillus fumigatus ATCC MYA-4609 (Q4WZ69), Aspergillus fumigatus FGSC A1100 (Q4WZ69), Aspergillus fumigatus Af293 (Q4WZ69)
Manually annotated by BRENDA team