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1.5.1.44: festuclavine dehydrogenase

This is an abbreviated version!
For detailed information about festuclavine dehydrogenase, go to the full flat file.

Wordmap for 1.5.1.44

Word Map on EC 1.5.1.44 Wordmap for 1.5.1.44

Reaction

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festuclavine
+
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NAD+
=
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6,8-dimethyl-6,7-didehydroergoline
+
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NADH
+
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H+

Synonyms

EasA, EasG, ergot alkaloid biosynthetic protein G, festuclavine synthase, festuclavine synthase I, festuclavine synthase II, FgaFS, ifgF1, ifgF2, isofumigaclavine biosynthesis cluster A protein F1, isofumigaclavine biosynthesis cluster A protein F2

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                EC 1.5.1.441.5.1.44 festuclavine dehydrogenase

Reference

Reference on EC 1.5.1.44 - festuclavine dehydrogenase

for references in articles please use BRENDA:EC1.5.1.44

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cheng, J.; Coyle, C.; Panaccione, D.; O’Connor, S.
Controlling a structural branch point in ergot alkaloid biosynthesis
J. Am. Chem. Soc.
132
12835-12837
2010
Aspergillus fumigatus
Manually annotated by BRENDA team
Xie, X.; Wallwey, C.; Matuschek, M.; Steinbach, K.; Li, S.M.
Formyl migration product of chanoclavine-I aldehyde in the presence of the old yellow enzyme FgaOx3 from Aspergillus fumigatus: a NMR structure elucidation
Magn. Reson. Chem.
49
678-681
2011
Aspergillus fumigatus
Manually annotated by BRENDA team
Wallwey, C.; Matuschek, M.; Xie, X.; Li, S.
Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3
Org. Biomol. Chem.
8
3500-3508
2010
Aspergillus fumigatus, Aspergillus fumigatus Af293
Manually annotated by BRENDA team
Matuschek, M.; Wallwey, C.; Xie, X.; Li, S.M.
New insights into ergot alkaloid biosynthesis in Claviceps purpurea: an agroclavine synthase EasG catalyses, via a non-enzymatic adduct with reduced glutathione, the conversion of chanoclavine-I aldehyde to agroclavine
Org. Biomol. Chem.
9
4328-4335
2011
Aspergillus fumigatus
Manually annotated by BRENDA team
Matuschek, M.; Wallwey, C.; Wollinsky, B.; Xie, X.; Li, S.
In vitro conversion of chanoclavine-I aldehyde to the stereoisomers festuclavine and pyroclavine controlled by the second reduction step
RSC Adv.
2
3662-3669
2012
Aspergillus fumigatus, Aspergillus fumigatus Af293, Claviceps purpurea, Penicillium commune (I6U936), Penicillium commune NRRL2033 (I6U936)
-
Manually annotated by BRENDA team
Gerhards, N.; Li, S.M.
A bifunctional old yellow enzyme from Penicillium roqueforti is involved in ergot alkaloid biosynthesis
Org. Biomol. Chem.
15
8059-8071
2017
Penicillium camemberti, Penicillium camemberti DSM 1233, Penicillium commune (I6U936), Penicillium roqueforti (W6QRI9), Penicillium roqueforti, Penicillium roqueforti FM164 (W6QRI9)
Manually annotated by BRENDA team
Martin, J.F.; Alvarez-Alvarez, R.; Liras, P.
Clavine alkaloids gene clusters of Penicillium and related fungi evolutionary combination of prenyltransferases, monooxygenases and dioxygenases
Genes (Basel)
8
342
2017
Aspergillus fumigatus (Q4WZ69), Aspergillus fumigatus Af293 (Q4WZ69), Aspergillus fumigatus ATCC MYA-4609 (Q4WZ69), Aspergillus fumigatus CBS 101355 (Q4WZ69), Aspergillus fumigatus FGSC A1100 (Q4WZ69), Penicillium camemberti, Penicillium commune (I6U936), Penicillium expansum (A0A0A2J928), Penicillium griseofulvum, Penicillium roqueforti (W6Q1E9), Penicillium roqueforti (W6QRI9), Penicillium roqueforti FM164 (W6Q1E9), Penicillium roqueforti FM164 (W6QRI9), Penicillium steckii (A0A1V6SJK0)
Manually annotated by BRENDA team