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1.5.1.48: 2-methyl-1-pyrroline reductase

This is an abbreviated version!
For detailed information about 2-methyl-1-pyrroline reductase, go to the full flat file.

Reaction

(R)-2-methylpyrrolidine
+
NADP+
=
2-methyl-1-pyrroline
 +
NADPH
 +
H+

Synonyms

(R)-imine reductase, (R)-IRED, PlRIR

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.48 2-methyl-1-pyrroline reductase

KM Value

KM Value on EC 1.5.1.48 - 2-methyl-1-pyrroline reductase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.155
1-methyl-3,4-dihydroisoquinoline
recombinant enzyme, pH and temperature not specified in the publication
1.88 - 3.52
2-methyl-1-pyrroline
0.481
2-methyl-3,4-dihydroisoquinolin-2-ium
recombinant enzyme, pH and temperature not specified in the publication
0.317
3,4-dihydroisoquinoline
recombinant enzyme, pH and temperature not specified in the publication
1.05
6-(4-methoxyphenyl)-2,3,4,5-tetrahydropyridine
recombinant enzyme, pH and temperature not specified in the publication
1.77
6-(prop-1-en-2-yl)-2,3,4,5-tetrahydropyridine
recombinant enzyme, pH and temperature not specified in the publication
0.244
6-(thiophen-2-yl)-2,3,4,5-tetrahydropyridine
recombinant enzyme, pH and temperature not specified in the publication
1.55
6-cyclohexyl-2,3,4,5-tetrahydropyridine
recombinant enzyme, pH and temperature not specified in the publication
0.371
6-methyl-2,3,4,5-tetrahydropyridine
recombinant enzyme, pH and temperature not specified in the publication
5.22
6-phenyl-2,3,4,5-tetrahydropyridine
recombinant enzyme, pH and temperature not specified in the publication
0.804
6-propyl-2,3,4,5-tetrahydropyridine
recombinant enzyme, pH and temperature not specified in the publication
0.0037
NADPH
-
30°C, pH 7.0