1.5.1.48: 2-methyl-1-pyrroline reductase

This is an abbreviated version!
For detailed information about 2-methyl-1-pyrroline reductase, go to the full flat file.

Reaction

Synonyms

(R)-imine reductase, (R)-IRED, PlRIR

ECTree

     1 Oxidoreductases

         1.5 Acting on the CH-NH group of donors

             1.5.1 With NAD⁺ or NADP⁺ as acceptor

                1.5.1.48 2-methyl-1-pyrroline reductase

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Results

in table

2

Activating Compound

3

AA Sequence

1

Application

2

Cloned(Commentary)

3

Cofactor

1

General Information

10

Inhibitors

12

kcat/KM [mM/s]

13

KM Value [mM]

2

Molecular Weight [Da]

6

Natural Substrates/ Products (Substrates)

5

Organism

16

PDB ID

4

pH Optimum

2

pH Range

3

Protein Variants

2

Purification (Commentary)

1

Reaction

5

Reference

2

Specific Activity [micromol/min/mg]

54

Substrates and Products (Substrate)

2

Subunits

5

Synonyms

1

Systematic Name

3

Temperature Optimum [°C]

1

Temperature Stability [°C]

11

Turnover Number [1/s]

pH Range

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pH Range on EC 1.5.1.48 - 2-methyl-1-pyrroline reductase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

10.2 - 11.7

Streptomyces sp.

-

pH 6.2: about 60% of maximal activity, pH 8.7: about 60% of maximal activity, oxidation of (R)-2-methylpyrrolidine

724593

6.2 - 8.7

Streptomyces sp.

-

pH 6.2: about 35% of maximal activity, pH 8.7: about 55% of maximal activity, reduction of 2-methyl-1-pyrroline

724593