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1.5.1.52: staphylopine dehydrogenase

This is an abbreviated version!
For detailed information about staphylopine dehydrogenase, go to the full flat file.

Reaction

staphylopine
+
NADP+
+
H2O
=
(2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate
+
pyruvate
+
NADPH
+
H+

Synonyms

cntM, SaODH, sav2468, staphylopine synthase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.52 staphylopine dehydrogenase

Systematic Name

Systematic Name on EC 1.5.1.52 - staphylopine dehydrogenase

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SYSTEMATIC NAME
IUBMB Comments
staphylopine:NADP+ oxidoreductase [(2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate]-forming
The enzyme, characterized from the bacterium Staphylococcus aureus, catalyses the last reaction in the biosynthesis of the metallophore staphylopine, which is involved in the acquisition of nickel, copper, and cobalt.