Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.5.1.53: methylenetetrahydrofolate reductase (NADPH)

This is an abbreviated version!
For detailed information about methylenetetrahydrofolate reductase (NADPH), go to the full flat file.

Reaction

5-methyltetrahydrofolate
+
NADP+
=
5,10-methylenetetrahydrofolate
+
NADPH
+
H+

Synonyms

5,10-CH2-H4folate reductase, 5,10-methylenetetrahydrofolate reductase, 5,10-methylenetetrahydrofolate reductase (FADH2), 5,10-methylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolic acid reductase, 5,10-methylenetetrahydropteroylglutamate reductase, 5-methyltetrahydrofolate:(acceptor) oxidoreductase, MET13, methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase, methylenetetrahydrofolate reductase, methylenetetrahydrofolate reductase (NADPH2), methylenetetrahydrofolic acid reductase, MTHFR, N5,10-methylenetetrahydrofolate reductase, N5,N10-methylenetetrahydrofolate reductase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.53 methylenetetrahydrofolate reductase (NADPH)

Posttranslational Modification

Posttranslational Modification on EC 1.5.1.53 - methylenetetrahydrofolate reductase (NADPH)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phosphoprotein
phosphorylation of up to 11 residues. Phosphorylation does not alter MTHFR kinetic parameters