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1.5.1.6: formyltetrahydrofolate dehydrogenase

This is an abbreviated version!
For detailed information about formyltetrahydrofolate dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.6

Reaction

10-formyltetrahydrofolate
+
NADP+
+
H2O
=
tetrahydrofolate
+
CO2
+
NADPH
+
H+

Synonyms

10-FDH, 10-formyl tetrahydrofolate:NADP oxidoreductase, 10-formyl-H2PtGlu:NADP oxidoreductase, 10-formyl-H4folate dehydrogenase, 10-formyltetrahydrofolate dehydrogenase, 10-fTHF dehydrogenase, 10-FTHFDH, ALDH1L1, ALDH1L2, dehydrogenase, formyltetrahydrofolate, FBP-CI, FBP-CI proteins, FDH, folate-binding proteins, cytosol I, More, mtFDH, N10-formyltetrahydrofolate dehydrogenase, proteins, folate-binding, cytosol I

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.6 formyltetrahydrofolate dehydrogenase

Molecular Weight

Molecular Weight on EC 1.5.1.6 - formyltetrahydrofolate dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
106000
-
4 * 106000, SDS-PAGE
108000
-
4 * 108000, SDS-PAGE
130000
x * 130000, green fluorescent protein fusion construct, SDS-PAGE
14500
-
4 * 14500, C-terminal domain, SDS-PAGE
320000
-
gel filtration
390000
-
gel filtration
393200
-
C707A mutant FDH, molecular size detector employing laser-light scattering methodology
398800
-
wild-type FDH, molecular size detector employing laser-light scattering methodology
400000
gel fitlration
413000
-
gel filtration, sedimentation analysis
440000
-
gel filtration
450000
-
nondenaturing PAGE
58000
-
C-terminal domain, gel filtration
90000
-
SDS-PAGE
91000
-
4 * 91000, three minor bands of 63000, 58000 and 39000, SDS-PAGE
92500
-
4 * 92500, SDS-PAGE
94000
-
x * 94000, SDS-PAGE
96000
98700
-
x * 98700, protein with 902 amino acids, calculated from cDNA
99000
99015
-
x * 99015, SDS-PAGE
99700
x * 99700, predicted