1.5.3.1: sarcosine oxidase (formaldehyde-forming)

This is an abbreviated version!
For detailed information about sarcosine oxidase (formaldehyde-forming), go to the full flat file.

Word Map on EC 1.5.3.1

1.5.3.1

flavin

fad

heterotetrameric

n-methylglycine

creatininase

amidinohydrolase

n-methyltryptophan

corynebacterial

flavinylation

diagnostics

analysis

medicine

Reaction

Synonyms

heterotetrameric sarcosine oxidase, L-pipecolate oxidase, L-pipecolic acid oxidase, monomeric sarcosine oxidase, MSOX, PSO, sarcosine : oxygen oxidoreductase (demethylating), sarcosine oxidase, sarcosine: O2 oxidoreductase, sarcosine:oxygen oxidoreductase (demethylating), SO, SO-U96, SOX, SoxA, trd_1773, TSOX

ECTree

1 Oxidoreductases

1.5 Acting on the CH-NH group of donors

1.5.3 With oxygen as acceptor

1.5.3.1 sarcosine oxidase (formaldehyde-forming)

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Results	in table
7443	AA Sequence
10	Application
1	CAS Registry Number
15	Cloned(Commentary)
48	Cofactor
11	Crystallization (Commentary)
3	General Information
1	General Stability
5	IC50 Value
83	Inhibitors
22	kcat/KM [mM/s]
63	KM Value [mM]
2	Localization
3	Metals/Ions
33	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
100	Organism
7	Pathway
55	PDB ID
13	pH Optimum
8	pH Range
7	pH Stability
48	Protein Variants
22	Purification (Commentary)
17	Reaction
4	Reaction Type
90	Reference
2	Renatured (Commentary)
4	Source Tissue
15	Specific Activity [micromol/min/mg]
3	Storage Stability
112	Substrates and Products (Substrate)
32	Subunits
31	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
10	Temperature Stability [°C]
44	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.5.3.1 - sarcosine oxidase (formaldehyde-forming)

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sarcosine + 5,6,7,8-tetrahydrofolate + O2

glycine + formaldehyde + H2O2

2 entries

sarcosine + H2O + O2

7 entries

sarcosine + H2O + O2

glycine + formaldehyde + H2O2

7 entries

sarcosine + H2O2 + O2

glycine + formaldehyde + H2O2

Bacillus sp. (in: Bacteria)

741596

sarcosine + O2 + H2O

formaldehyde + glycine + H2O2

3 entries

additional information

Corynebacterium sp.

heterotetrameric sarcosine oxidase is a flavoprotein that catalyses the oxidative demethylation of sarcosine to generate glycine, hydrogen peroxide and formaldehyde or 5,10-methylenetetrahydrofolate, depending on the availability of tetrahydrofolate. The amine proton of sarcosine is transferred to the unprotonated Lys residue in the enzyme-substrate complex

725317