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1.5.3.13: N1-acetylpolyamine oxidase

This is an abbreviated version!
For detailed information about N1-acetylpolyamine oxidase, go to the full flat file.

Word Map on EC 1.5.3.13

Reaction

N1-acetylspermidine
+
O2
 +
H2O
=
putrescine
 +
3-acetamidopropanal
 +
H2O2

Synonyms

APAO, AtPAO5, Bjpao2, EC 1.5.3.11, HPAO, hPAO-1, More, MPAO, N1-acetyl polyamine oxidase, N1-acetylpolyamine oxidase, PAO, PAO5, PAOh1, PAOX, polyamine oxidase, SelPAO5

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.13 N1-acetylpolyamine oxidase

KM Value

KM Value on EC 1.5.3.13 - N1-acetylpolyamine oxidase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.06
3-[4-(3-aminopropoxy)butoxy]-N-benzylpropan-1-amine
pH 7.5, 37°C
-
0.016
alpha-methylspermidine
-
addition of 5 mM benzyldehyde, hPAO
0.011 - 0.019
alpha-methylspermine
0.0036
N-[(2R)-4-[(4-aminobutyl)amino]butan-2-yl]pyridine-4-carboxamide
pH 9, 25°C
-
0.0008
N-[(2S)-4-[(4-aminobutyl)amino]butan-2-yl]pyridine-4-carboxamide
pH 9, 25°C
-
0.0027
N1,N11-diacetylnorspermine
-
-
0.001
N1-(3-[[(thiophen-2-yl)methyl]amino]propyl)octane-1,8-diamine
pH 7.5, 37°C
-
0.0021 - 0.028
N1-acetylspermidine
0.00085 - 0.382
N1-acetylspermine
0.0012
N1-benzoyl-(R)-alpha-methylspermidine
pH 9, 25°C
-
0.0002
N1-benzoyl-(S)-alpha-methylspermidine
pH 9, 25°C
-
0.025
N1-benzyldodecane-1,12-diamine
pH 7.5, 37°C
0.0002
N1-benzylspermine
pH 7.5, 37°C
-
0.0016 - 0.002
N1-phenyl-(R)-alpha-methylspermidine
-
0.000025
N1-[(naphthalen-2-yl)methyl]spermine
pH 7.5, 37°C
-
0.00052
N1-[(pyridin-2-yl)methyl]spermine
pH 7.5, 37°C
-
0.089
N1-[(thiophen-2-yl)methyl]dodecane-1,12-diamine
pH 7.5, 37°C
-
0.000044
N1-[(thiophen-2-yl)methyl]spermine
pH 7.5, 37°C
-
0.015
spermidine
-
addition of 5 mM benzyldehyde, hPAO
0.0093 - 11
spermine
additional information
additional information
-