18.104.22.168: 4-methylaminobutanoate oxidase (formaldehyde-forming)
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gamma-N-methylaminobutanoate oxidase, gamma-N-methylaminobutyrate oxidase, mabO
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General Information on EC 22.214.171.124 - 4-methylaminobutanoate oxidase (formaldehyde-forming)
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in nicotine breakdown, two alternative pathways for the final steps in the catabolism of 4-methylaminobutanoate could be identified. 4-Methylaminobutanoate may be demethylated to gamma-N-aminobutyrate by gamma-N-methylaminobutanoate oxidase, EC 126.96.36.199. In an alternative pathway, amine oxidase, EC 188.8.131.52, removes methylamine from 4-methylaminobutanoate with the formation of succinic semialdehyde. Kinetic analyses suggest that demethylation predominates over deamination of 4-methylaminobutanoate