1.5.3.5: (S)-6-hydroxynicotine oxidase

This is an abbreviated version!
For detailed information about (S)-6-hydroxynicotine oxidase, go to the full flat file.

Word Map on EC 1.5.3.5

1.5.3.5

arthrobacter

6-hydroxy-d-nicotine

nicotinovorans

oxidans

flavin

fad

flavoenzyme

nicotine-degrading

monoamine

flavoproteins

hydride

6-hydroxypseudooxynicotine

dehydrogenation

pseudooxynicotine

d-specific

pyrrolidine

dithionite-reduced

carbon-carbon

self-formed

fad-binding

s-nicotine

l-enantiomer

fitzpatrick

carbon-nitrogen

isoalloxazine

6-hdno

substrate-reduced

Reaction

1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one

Synonyms

6-HLNO, 6-hydroxy-L-nicotine oxidase, 6-hydroxy-L-nicotine:oxygen oxidoreductase, 6HLNO, flavoprotein nicotine oxidoreductase, L-6-hydroxynicotine oxidase, LHNO, MAO, NdpB, NicA2, NOX, VppB

ECTree

1 Oxidoreductases

1.5 Acting on the CH-NH group of donors

1.5.3 With oxygen as acceptor

1.5.3.5 (S)-6-hydroxynicotine oxidase

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Results	in table
1	Activating Compound
6	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
23	Cofactor
6	Crystallization (Commentary)
2	Expression
13	General Information
22	Inhibitors
23	kcat/KM [mM/s]
3	Ki Value [mM]
28	KM Value [mM]
1	Localization
2	Metals/Ions
6	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
34	Organism
3	Pathway
14	PDB ID
10	pH Optimum
1	pH Range
5	pH Stability
1	Posttranslational Modification
13	Protein Variants
8	Purification (Commentary)
4	Reaction
3	Reaction Type
29	Reference
2	Specific Activity [micromol/min/mg]
1	Storage Stability
48	Substrates and Products (Substrate)
10	Subunits
32	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Range [°C]
8	Temperature Stability [°C]
19	Turnover Number [1/s]

pH Stability

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pH Stability on EC 1.5.3.5 - (S)-6-hydroxynicotine oxidase

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Shinella sp.

A0A075BSX9

40°C, 1 h, about 30% loss of activity

741686

2 entries

6 - 9

Paenarthrobacter nicotinovorans

very unstable under pH 6

392438

7 - 8

Shinella sp.

A0A075BSX9

40°C, 1 h, no loss of activity

741686