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1.5.3.6: (R)-6-hydroxynicotine oxidase

This is an abbreviated version!
For detailed information about (R)-6-hydroxynicotine oxidase, go to the full flat file.

Word Map on EC 1.5.3.6

Reaction

(R)-6-hydroxynicotine
+
H2O
+
O2
=
1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one
+
H2O2

Synonyms

6-HDNO, 6-hydroxy-D-nicotine oxidase, D-6-hydroxynicotine oxidase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.6 (R)-6-hydroxynicotine oxidase

KCat KM Value

KCat KM Value on EC 1.5.3.6 - (R)-6-hydroxynicotine oxidase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4
(R)-4-(1-methylpyrrolidine-2-yl)phenol, (R)-6-chloronicotine
Q8GAG1
wild-type, pH 8, 25°C
-
0.1 - 380
(R)-6-hydroxynicotine
6.5 - 24
(R)-6-hydroxynornicotine
-
0.15
(R)-nicotine
Q8GAG1
wild-type, pH 8, 25°C
3.2 - 39
O2