1.5.4.1: pyrimidodiazepine synthase

This is an abbreviated version!
For detailed information about pyrimidodiazepine synthase, go to the full flat file.

Reaction

2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one
+
glutathione disulfide
+
H2O
=
6-pyruvoyltetrahydropterin
+ 2 glutathione

Synonyms

More, PDA synthase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.4 With a disulfide as acceptor
                1.5.4.1 pyrimidodiazepine synthase

Reference

Reference on EC 1.5.4.1 - pyrimidodiazepine synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wiederrecht, G.J.; Brown, G.M.
Purification and properties of the enzymes from Drosophila melanogaster that catalyze the conversion of dihydroneopterin triphosphate to the pyrimidodiazepine precursor of the drosopterins
J. Biol. Chem.
259
14121-14127
1984
Drosophila melanogaster
Manually annotated by BRENDA team
Giordano, E.; Peluso, I.; Rendina, R.; Digilio, A.; Furia, M.
The clot gene of Drosophila melanogaster encodes a conserved member of the thioredoxin-like protein superfamily
Mol. Genet. Genomics
268
692-697
2003
Drosophila melanogaster (Q9VMQ9)
Manually annotated by BRENDA team
Kim, J.; Suh, H.; Kim, S.; Kim, K.; Ahn, C.; Yim, J.
Identification and characteristics of the structural gene for the Drosophila eye colour mutant sepia, encoding PDA synthase, a member of the Omega class glutathione S-transferases
Biochem. J.
398
451-460
2006
Drosophila melanogaster
Manually annotated by BRENDA team