1.5.4.1: pyrimidodiazepine synthase

This is an abbreviated version!
For detailed information about pyrimidodiazepine synthase, go to the full flat file.

Reaction

2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one
+
glutathione disulfide
+
H2O
=
6-pyruvoyltetrahydropterin
+ 2 glutathione

Synonyms

More, PDA synthase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.4 With a disulfide as acceptor
                1.5.4.1 pyrimidodiazepine synthase

Substrates Products

Substrates Products on EC 1.5.4.1 - pyrimidodiazepine synthase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
6-pyruvoyl-tetrahydropterin + glutathione
pyrimidodiazepine + glutathione disulfide
show the reaction diagram
6-pyruvoyltetrahydropterin + glutathione
glutathione disulfide + pyrimidodiazepine
show the reaction diagram
dihydroneopterin triphosphate + glutathione
?
show the reaction diagram
-
-
-
-
-
glutathione disulfide + pyrimidodiazepine
6-pyruvoyltetrahydropterin + glutathione
show the reaction diagram
-
-
-
-
r
pyruvoyltetrahydropterin + glutathione
2-amino-4-oxo-6-acetyl-7,8-dihydro-3H,9H-pyrimido[4,5-b]-[1,4]diazepine
show the reaction diagram
-
-
PDA
?