Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.5.4.1: pyrimidodiazepine synthase

This is an abbreviated version!
For detailed information about pyrimidodiazepine synthase, go to the full flat file.

Reaction

2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one
+
glutathione disulfide
+
H2O
=
6-pyruvoyltetrahydropterin
+ 2 glutathione

Synonyms

More, PDA synthase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.4 With a disulfide as acceptor
                1.5.4.1 pyrimidodiazepine synthase

Systematic Name

Systematic Name on EC 1.5.4.1 - pyrimidodiazepine synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SYSTEMATIC NAME
IUBMB Comments
2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)
In the reverse direction, the reduction of 6-pyruvoyl-tetrahydropterin is accompanied by the opening of the 6-membered pyrazine ring and the formation of the 7-membered diazepine ring. The pyrimidodiazepine formed is an acetyldihydro derivative. Involved in the formation of the eye pigment drosopterin in Drosophila melanogaster.