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1.5.8.4: dimethylglycine dehydrogenase

This is an abbreviated version!
For detailed information about dimethylglycine dehydrogenase, go to the full flat file.

Word Map on EC 1.5.8.4

Reaction

N,N-dimethylglycine
+
5,6,7,8-tetrahydrofolate
 +
electron-transfer flavoprotein
=
sarcosine
 +
5,10-methylenetetrahydrofolate
 +
reduced electron-transfer flavoprotein

Synonyms

Csal_0990, DdhC, DMGDH, EC 1.5.99.2, Me2GlyDH, mMe2GlyDH, N,N-dimethylglycine oxidase, pMe2GlyDH

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.8 With a flavin or flavoprotein as acceptor
                1.5.8.4 dimethylglycine dehydrogenase

Expression

Expression on EC 1.5.8.4 - dimethylglycine dehydrogenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
during the process of intestine regeneration, there are significant differences in metabolism between regenerative intestines at 3, 7, and 14 days post evisceration and normal intestines. Genes encoding betaine-aldehyde dehydrogenase, betaine-homocysteine S-methyltransferase 1, and dimethylglycine dehydrogenase are differentially expressed to regulate the levels of betaine and N,N-dimethylglycine during intestine regeneration
-
enzyme expression is decreased in hepatocellular carcinoma
expression is decreased in hepatocellular carcinoma