1.6.1.3: NAD(P)+ transhydrogenase
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For detailed information about NAD(P)+ transhydrogenase, go to the full flat file.
Word Map on EC 1.6.1.3
Reaction
Synonyms
mitochondrial NADPH->NAD transhydrogenase, NAD(P) transhydrogenase, NADPH:NAD transhydrogenase, nicotinamide nucleotide transhydrogenase, NNT, proton-translocating transhydrogenase domain III, pyridine nucleotide transhydrogenase, SthA
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General Information
General Information on EC 1.6.1.3 - NAD(P)+ transhydrogenase
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GENERAL INFORMATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
malfunction
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mice lacking functional enzyme are characterized by lower energy expenditure rates, consistent with their well-known susceptibility to diet-induced obesity
physiological function
physiological function
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the activity of NAD(P) transhydrogenase is a key element in determining the redox state of NADP and thus of Ca2+ retention and efflux from mitochondria
physiological function
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the enzyme of adult Hymenolepis diminuta physiologically couples matrix-localized, NADP-specific malic enzyme with NADH-dependent anaerobic electron transport. The enzyme acts in the translocation of protons from the matrix to the intermembrane space mitochondrial compartment
