1.6.3.4: NADH oxidase (H2O-forming)
This is an abbreviated version!
For detailed information about NADH oxidase (H2O-forming), go to the full flat file.
Reaction
2 NADH + 2 H+ + = 2 NAD+ + 2 H2O
Synonyms
H2O-forming NADH oxidase, LrNox, NADH oxidase, nicotinamide adenine dinucleotide oxidase, NOX, Nox-2, NoxA, NoxE, SpNox, water-forming NADH oxidase, YODC
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General Information
General Information on EC 1.6.3.4 - NADH oxidase (H2O-forming)
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malfunction
the inability of the nox2 mutant to grow aerobically is mainly due to an underlying defect in fatty acid biosynthesis. NAD+ depletion in the nox2 mutant results in reduced acetyl-CoA production, which perturbs fatty acid biosynthesis and hence blocks growth in aerobiosis
metabolism
physiological function
the enzyme can regulate the metabolism during aerobic fermentation in Saccharomyces cerevisiae, thereby protecting cells against several stresses
metabolism
Lactococcus cremoris MG1363
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the enzyme can regulate the metabolism during aerobic fermentation in Saccharomyces cerevisiae, thereby protecting cells against several stresses
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the enzyme is essential for aerobic growth and oxidative stress resistance in conventional culture media. The enzyme facilitates adaptation of group B Streptococci to aerobic conditions encountered during infection
physiological function
the enzyme is involved in oxygen metabolism
physiological function
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the enzyme is involved in oxygen metabolism
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