1.6.5.9: NADH:quinone reductase (non-electrogenic)
This is an abbreviated version!
For detailed information about NADH:quinone reductase (non-electrogenic), go to the full flat file.
Word Map on EC 1.6.5.9
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1.6.5.9
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ndh-2
-
hydrogenases
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proton-translocating
-
ubiquinone-1
-
hqno
-
2-heptyl-4-hydroxyquinoline-n-oxide
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single-subunit
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deamino-nadh
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na+-translocating
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rotenone-sensitive
- 1.6.5.9
- ndh-2
- hydrogenases
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proton-translocating
- ubiquinone-1
- hqno
- 2-heptyl-4-hydroxyquinoline-n-oxide
-
single-subunit
- deamino-nadh
-
na+-translocating
-
rotenone-sensitive
Reaction
Synonyms
alternative external NADH dehydrogenase, alternative NADH dehydrogenase, alternative NADH-quinone oxidoreductase, alternative NADH:quinone reductase, alternative NADH:ubiquinone oxidoreductase, alternative rotenone-insensitive NADH:Q oxidoreductase, CathTA2_0279, Cgl1465, EC 1.6.5.11, EC 1.6.99.5, external alternative NADH dehydrogenase, external alternative NADH: ubiquinone oxidoreductase, external NADH:ubiquinone oxidoreductase, external rotenone-insensitive NADH dehydrogenase, internal alternative NADH dehydrogenase, internal alternative NADH: ubiquinone oxidoreductase, internal alternative NADH:ubiquinone oxidoreductase, Internal NADH dehydrogenase, internal rotenone-insensitive NADH dehydrogenase, NADH dehydrogenase, NADH dehydrogenase-2, NADH-ubiquinone oxidoreductase, NADH: ubiquinone oxidoreductase, NADH: ubiquinone-2 oxidoreductase, NADH:Q6 oxidoreductase, NADH:ubiquinone reductase (non-electrogenic), NADHQ2, NDA, NDB, NdeA, NdeA-B, NDH, NDH-2, NDH-II, NDH2, NDH2e, NDH2i, Ndi1, NdiA, NDX, non-proton pumping type II NADH dehydrogenase, non-proton-pumping NADH dehydrogenase, rotenone-insensitive NADH dehydrogenase, rotenone-insensitive NADH-ubiquinone oxidoreductase
ECTree
1.6.5.9 NADH:quinone reductase (non-electrogenic)Advanced search results
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Substrates Products
Substrates Products on EC 1.6.5.9 - NADH:quinone reductase (non-electrogenic)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
NADH + H+ + 2,6-dichlorophenolindophenol
NAD+ + reduced 2,6-dichlorophenolindophenol
-
-
-
-
?
NADH + H+ + 2-azido-5-geranyl-3-methoxy-6-methyl-1,4-benzoquinone
NAD+ + 2-azido-5-geranyl-3-methoxy-6-methyl-1,4-benzoquinol
-
-
-
?
NADH + H+ + duroquinone
NAD+ + duroquinol
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49% activity compared to ubiquinone-1
-
-
?
NADH + H+ + N-(6-[[(4E,8E)-10-(4-azido-5-methoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)-4,8-dimethyldeca-4,8-dien-1-yl]amino]-6-oxohexyl)-6-([5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl]amino)hexanamide
NAD+ + N-(6-[[(4E,8E)-10-(4-azido-3,6-dihydroxy-5-methoxy-2-methylcyclohexa-1,4-dien-1-yl)-4,8-dimethyldeca-4,8-dien-1-yl]amino]-6-oxohexyl)-6-([5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl]amino)hexanamide
-
-
-
?
NADH + H+ + N-[(4E,8E)-10-(4-azido-5-methoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)-4,8-dimethyldeca-4,8-dien-1-yl]-6-([5-[(3aS,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl]amino)hexanamide
NAD+ + N-[(4E,8E)-10-(4-azido-3,6-dihydroxy-5-methoxy-2-methylcyclohexa-1,4-dien-1-yl)-4,8-dimethyldeca-4,8-dien-1-yl]-6-([5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl]amino)hexanamide
-
-
-
?
NADH + H+ + N-[2-[2-(2-[[(4E,8E)-10-(4-azido-5-methoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)-4,8-dimethyldeca-4,8-dien-1-yl]oxy]ethoxy)ethoxy]ethyl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
NAD+ + N-[2-[2-(2-[[(4E,8E)-10-(4-azido-3,6-dihydroxy-5-methoxy-2-methylcyclohexa-1,4-dien-1-yl)-4,8-dimethyldeca-4,8-dien-1-yl]oxy]ethoxy)ethoxy]ethyl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
-
-
-
?
2 ferricyanide + NADH
2 ferrocyanide + NAD+ + H+
-
15% activity compared to ubiquinone-1
-
-
?
NADH + H+ + 2,6-dichloroindophenol
NAD+ + reduced 2,6-dichloroindophenol
-
17% activity compared to ubiquinone-1
-
-
?
NADH + H+ + 2,6-dichloroindophenol
NAD+ + reduced 2,6-dichloroindophenol
-
-
-
-
?
NADH + H+ + menadione
NAD+ + menadiol
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47% activity compared to ubiquinone-1
-
-
?
NADH + H+ + ubiquinone-2
NAD+ + ubiquinol-2
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ubiquinone is the best electron acceptor
-
-
?
additional information
?
-
-
NDH-II does not pump protons
-
-
?
additional information
?
-
-
the yeast enzyme is a two-electron reaction enzyme
-
-
?
additional information
?
-
-
NAD+ binds in the second Rossmann domain in a predominantly positively charged cleft, with the nicotinamide ring approaching the re-face of the FAD
-
-
?
additional information
?
-
-
the alternative NADH:ubiquinone oxidoreductase does not contribute to the proton gradient across the respiratory membrane
-
-
?
additional information
?
-
-
alternative NADH:ubiquinone oxidoreductase does not pump protons across the inner mitochondrial membrane
-
-
?
additional information
?
-
-
NDH2 does not translocate protons across the inner mitochondrial membrane
-
-
?
additional information
?
-
NDH2e is a peripheral single-subunit oxido-reductase that does not pump protons
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-
?
additional information
?
-
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NDH2e is a peripheral single-subunit oxido-reductase that does not pump protons
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-
?
additional information
?
-
-
alternative NADH:ubiquinone oxidoreductase does not pump protons across the inner mitochondrial membrane
-
-
?
