1.7.1.6: azobenzene reductase

This is an abbreviated version!
For detailed information about azobenzene reductase, go to the full flat file.

Word Map on EC 1.7.1.6

Reaction

N,N-dimethyl-1,4-phenylenediamine
+
aniline
+ 2 NADP+ =
4-(dimethylamino)azobenzene
+ 2 NADPH + 2 H+

Synonyms

acpD, aerobic azoreductase, Azo 1, azo dye reductase, azo reductase, azo-dye reductase, AzoA, AzoB, AzoC, AzoEF1, AzoI, AzoII, AzoR, AzoR1, azoreductase, azoreductase 1, azoreductase B, azoreductase C, AZR, AzrA, AzrB, AzrC, AzrG, AzrS, bsAzoR, BTI1, class 1 azoreductase, class 2 azoreductase, dibromopropylaminophenylazobenzoic azoreductase, dimethylaminobenzene reductase, EC 1.6.6.7, ecAzoR, EF0404, efAzoR, EF_0404, flavin mononucleotide-containing azoreductase, flavin-dependent azoreductase, FMN-dependent NAD(P)H azoreductase, FMN-dependent NAD(P)H nitroreductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase, methyl red azoreductase, N,N-dimethyl-4-phenylazoaniline azoreductase, NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase, NADH driven FMN dependent azoreductase, NADH-azoreductase, NADPH-dependent azoreductase Azr, NADPH-flavin azoreductase, NADPH2-dependent azoreductase, NC-reductase, new Coccine (NC)-reductase, nicotinamide adenine dinucleotide (phosphate) azoreductase, Orange I azoreductase, Orange II azoreductase, oxygen insensitive intracellular azoreductase, p-aminoazobenzene reductase, p-dimethylaminoazobenzene azoreductase, paAzoR1, PAMD_1, PpAzoR, reductase, azobenzene, rsAzoR, SO 4396

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.6 azobenzene reductase

Inhibitors

Inhibitors on EC 1.7.1.6 - azobenzene reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3,3'-methylene-bis(4-hydroxycoumarin)
-
dicoumarol
4-Dimethylaminoazobenzene
-
-
Ag+
-
1 mM, 92% inhibition
Al3+
-
2 mM, 47.9% residual activity
cetyl dimethylethyl ammonium bromide
-
Cetylpyridinium chloride
-
Cibacron blue
CO
-
noncompetitive vs. amaranth
dicoumarol
fatty acids
-
oxidized unsaturated
Fe3+
-
1 mM, 85% inhibition
ferric chloride
-
1 mM leads to 80% inhibition, 2.5 mM leads to 98% inhibition
iodoacetamide
A0A073KHN9
loss of 30.6% activity at 10% v/v
Methyl red
-
substrate inhibition above 0.08 mM
Mg2+
-
2 mM, 81% residual activity
NaCl
-
more than 40% of maximum activity up to 2.5 M
Orange I
-
substrate inhibition
Orange II
-
substrate inhibition at high concentration
oxygen
-
presence of oxygen in the assay reduces the activity
sodium dodecylsulfate
-
1 mM, 53% residual activity
tetradecylammonium bromide
-
additional information
-