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1.7.1.B2: aromatic nitroreductase [NAD(P)H]

This is an abbreviated version!
For detailed information about aromatic nitroreductase [NAD(P)H], go to the full flat file.

Reaction

an aromatic amine
+ 3 NAD(P)+ + 2 H2O =
an aromatic nitrate
+ 3 NAD(P)H + 3 H+

Synonyms

NfnB, NfsB, NfsB_Ec, NfsB_Pa, NprA, oxygen-insensitive nitroreductase (NAD(P)H), YfkO

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.B2 aromatic nitroreductase [NAD(P)H]

KCat KM Value

KCat KM Value on EC 1.7.1.B2 - aromatic nitroreductase [NAD(P)H]

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
290 - 5389
2,4,6-trinitrotoluene
640
2,4-dinitrotoluene
at pH 8.0 and 30°C
43 - 57
2,6-dinitrotoluene
0.055 - 0.31
2-(2-methyl-5-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide
-
26 - 206
2-amino-4,6-dinitrotoluene
4 - 31
4-amino-2,6-dinitrotoluene