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1.7.1.B3: aromatic nitroreductase [NADPH]

This is an abbreviated version!
For detailed information about aromatic nitroreductase [NADPH], go to the full flat file.

Word Map on EC 1.7.1.B3

Reaction

an aromatic amine
+ 3 NADP+ + 2 H2O =
an aromatic nitrate
 + 3 NADPH + 3 H+

Synonyms

ipa-43d, More, NADPH-FMN reductase, NADPH-nitrofurazone reductase, NfrA1, NfsA, nitro/flavin reductase, nitrofurazone reductase, nitroreductase A, non-luminescent-bacterial NfsA/Frp-type enzyme, NR-A, ORF 17150, oxygen-insensitive NAD(P)H:nitroreductases, oxygen-insensitive nitroreductase (NADPH)

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.B3 aromatic nitroreductase [NADPH]

Turnover Number

Turnover Number on EC 1.7.1.B3 - aromatic nitroreductase [NADPH]

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
110
2,4,6-trinitrophenyl N-methylnitramine
-
at pH 7.0 and 25°C
-
0.67 - 135.1
2,4,6-trinitrotoluene
0.7 - 24.94
2,4-dinitrotoluene
12.36
2-amino-4,6-dinitrotoluene
pH 7.0, 37°C, recombinant His6-tagged enzyme
1.05
4-amino-2,6-dinitrotoluene
pH 7.0, 37°C, recombinant His6-tagged enzyme
59.4
4-Nitroacetophenone
-
at pH 7.0 and 25°C
64.3
4-nitrobenzoic acid
-
at pH 7.0 and 25°C
1.08 - 36.64
5-(aziridin-1-yl)-2,4-dinitrobenzamide
55
m-dinitrobenzene
-
pH 7.0, 25°C
0.46 - 16.3
NADPH
180
nifuroxime
-
pH 7.0, 25°C
14 - 14.2
nitrobenzene
136
Nitrofurantoin
-
pH 7.0, 25°C
0.8 - 19.37
nitrofurazone
60
o-dinitrobenzene
-
pH 7.0, 25°C
27
p-dinitrobenzene
-
pH 7.0, 25°C
59
p-nitroacetophenone
-
pH 7.0, 25°C
30
p-nitrobenzaldehyde
-
pH 7.0, 25°C
64
p-nitrobenzoic acid
-
pH 7.0, 25°C
85
tetryl
-
pH 7.0, 25°C