1.7.2.1: nitrite reductase (NO-forming)

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For detailed information about nitrite reductase (NO-forming), go to the full flat file.

Word Map on EC 1.7.2.1

1.7.2.1

anemia

mellitus

glycated

hematocrit

erythrocyte

hematological

women

arterial

glycemic

transfusion

platelet

children

albumin

cardiovascular

cholesterol

postoperative

ferritin

fetal

sickle

creatinine

preoperative

bleeding

cardiac

erythropoietin

hypertension

heme

triglyceride

hemorrhage

admission

systolic

venous

demographic

january

hemolysis

c-reactive

erythroid

hypoglycemia

comorbidities

reticulocyte

hemodialysis

transferrin

admitted

hemodynamic

placebo

diastolic

intraoperative

outpatient

anthropometric

bilirubin

waist

medicine

analysis

Reaction

+ 2 H+

Synonyms

AcNIR, AfNiR, AniA, AxNiR, BRAO375_2740002, C551-O2 oxidoreductase, cd1 nitrite reductase, cd1NiR, cNOR, copper-containing dissimilatory nitrite reductase, copper-containing nitrite reductase, Cu-NIR, Cu-NirK, CuNIR, cytochrome c-551:O2, NO2- oxidoreductase, cytochrome cd, cytochrome cd1 nitrite reductase, cytochrome oxidase, dissimilatory nitrite reductase, dissimilatory nitrite reductase cytochrome cd1, EC 1.6.6.5, EC 1.7.99.3, EC 1.9.3.2, GK0767, GtNiR, HdNIR, hemoglobin, HydNIR, HYPDE_25578, KSU1_D0929, mARC1, mARC2, mitochondrial amidoxime reducing component, MRA2164, NiR, NiR-Pa, NirK, NirS, nitrite reductase, oxidase, Pseudomonas cytochrome, PaNiR, PNR, Pseudomonas cytochrome oxidase, PsNiR, reductase, nitrite (cytochrome), Rpic_4015, S58_68210

ECTree

1 Oxidoreductases

1.7 Acting on other nitrogenous compounds as donors

1.7.2 With a cytochrome as acceptor

1.7.2.1 nitrite reductase (NO-forming)

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Results	in table
4	Activating Compound
10578	AA Sequence
2	Application
1	CAS Registry Number
37	Cloned(Commentary)
59	Cofactor
30	Crystallization (Commentary)
108227	Disease/ Diagnostics
2	Expression
54	General Information
1	General Stability
32	Inhibitors
4	kcat/KM [mM/s]
5	Ki Value [mM]
100	KM Value [mM]
28	Localization
50	Metals/Ions
47	Molecular Weight [Da]
55	Natural Substrates/ Products (Substrates)
189	Organism
10	Pathway
293	PDB ID
25	pH Optimum
5	pH Range
3	pI Value
1	Posttranslational Modification
83	Protein Variants
41	Purification (Commentary)
30	Reaction
3	Reaction Type
164	Reference
1	Renatured (Commentary)
12	Source Tissue
26	Specific Activity [micromol/min/mg]
4	Storage Stability
183	Substrates and Products (Substrate)
68	Subunits
148	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
86	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.7.2.1 - nitrite reductase (NO-forming)

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acetate

Alcaligenes faecalis

P38501

weak, mixed-type inhibition, inhibition mode, overview

azide

CN-

20% residual activity

695769

diethyldithiocarbamate

EDTA

formate

weak mixed-type inhibition, inhibition mode, overview

696259

KCN

4 entries

methylhydrazine

Pseudomonas aeruginosa

irreversible

665461

NADH

Mycobacterium tuberculosis

A5U4H6

5 mM, 92.3% inhibition

765787

NaN3

Paracoccus denitrificans

1 mM, 60% inhibition

644782

NH2OH

Paracoccus denitrificans

1 mM, 50% inhibition

nitrate

nitrite

nitrous oxide

binding mode, overview

696259

oxidized cytochrome c

Pseudomonas aeruginosa

395067

phenylhydrazine

Pseudomonas aeruginosa

irreversible

665461

Tungsten

Homo sapiens

Q5VT66, Q969Z3

replacement of molybdenum by tungsten abolishes NO formation

742855

Urea

Cereibacter sphaeroides

4 M, 60% inhibition

644779

additional information

3 entries