1.7.2.3: trimethylamine-N-oxide reductase

This is an abbreviated version!
For detailed information about trimethylamine-N-oxide reductase, go to the full flat file.

Word Map on EC 1.7.2.3

1.7.2.3

twin-arginine

molybdoenzyme

tord

tat-dependent

cofactor-containing

dmsabc

Reaction

+ 2 (ferricytochrome c)-subunit +

+ 2 (ferrocytochrome c)-subunit + 2 H+

Synonyms

EC 1.6.6.9, More, reductase, trimethylamine N-oxide, TMAO reductase, TOR, TorA, TorD, torECA gene product, TorECAD, TorZ, trimethylamine N-oxide reductase, trimethylamine oxide reductase

ECTree

1 Oxidoreductases

1.7 Acting on other nitrogenous compounds as donors

1.7.2 With a cytochrome as acceptor

1.7.2.3 trimethylamine-N-oxide reductase

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Results	in table
3	Activating Compound
4684	AA Sequence
1	Application
1	CAS Registry Number
19	Cloned(Commentary)
20	Cofactor
3	Crystallization (Commentary)
4	Expression
4	General Information
2	General Stability
34	Inhibitors
51	KM Value [mM]
21	Localization
21	Metals/Ions
30	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
52	Organism
1	Oxidation Stability
3	Pathway
10	PDB ID
7	pH Optimum
2	pH Stability
5	Protein Variants
22	Purification (Commentary)
2	Reaction
3	Reaction Type
51	Reference
1	Source Tissue
44	Specific Activity [micromol/min/mg]
5	Storage Stability
124	Substrates and Products (Substrate)
18	Subunits
44	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
9	Temperature Stability [°C]
37	Turnover Number [1/s]

Expression

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Expression on EC 1.7.2.3 - trimethylamine-N-oxide reductase

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serum enzyme level is elevated in chronic kidney disease mice and patients with chronic kidney disease

uncultured bacterium

764049

the expression level and enzymatic activity of subunit TorA is up-regulated by elevated pressure (over 2fold at 30 MPa)

3 entries