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1.7.3.3: factor-independent urate hydroxylase

This is an abbreviated version!
For detailed information about factor-independent urate hydroxylase, go to the full flat file.

Word Map on EC 1.7.3.3

Reaction

Urate
+
O2
 +
H2O
=
5-hydroxyisourate
 +
H2O2

Synonyms

AaUO, AgUOX, dHU-wPU, ELITEK, Fasturtec, MVSM, N-35, Nodule specific uricase, Nodulin 35, Nodulin 35 homolog, Non-symbiotic uricase, oxidase, urate, Pucl, Rasburicase, Uaz, Uox, Urate oxidase, urate oxidoreductase, UriA, uric acid oxidase, uricase, uricase II, Uricoenzyme, Uricozyme

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.3 With oxygen as acceptor
                1.7.3.3 factor-independent urate hydroxylase

Source Tissue

Source Tissue on EC 1.7.3.3 - factor-independent urate hydroxylase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
strain CGMCC 2.120 is used as source of uricase gene
Manually annotated by BRENDA team
-
wild-type and PEX5-defective CHO cell lines each stable producing the enzyme
Manually annotated by BRENDA team
-
no uricase is detected in mycelium grown in minimal medium containing NH4Cl as sole nitrogen source. Uricase activity is increased 10fold to 40fold under derepression conditions and is induced by exogenous uric acid
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
additional information