1.8.1.14: CoA-disulfide reductase

This is an abbreviated version!
For detailed information about CoA-disulfide reductase, go to the full flat file.

Word Map on EC 1.8.1.14

Reaction

2 CoA +

NADP+
=
CoA-disulfide
+
NADPH
+
H+

Synonyms

BACoADR, BB0728, CoA disulfide reductase, CoA-disulfide reductase (NADH), CoA-disulfide reductase (NADH2), CoADR, coenzyme A disulfide reductase, coenzyme A disulphide reductase, coenzyme A-disulfide reductase, NADH2:CoA-disulfide oxidoreductase, NADH:CoA-disulfide oxidoreductase, PH0572

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.14 CoA-disulfide reductase

Systematic Name

Systematic Name on EC 1.8.1.14 - CoA-disulfide reductase

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SYSTEMATIC NAME
IUBMB Comments
CoA:NADP+ oxidoreductase
A flavoprotein. Not identical with EC 1.8.1.6 (cystine reductase), EC 1.8.1.7 (glutathione-disulfide reductase) or EC 1.8.1.13 (bis-gamma-glutamylcystine reductase). The enzyme from the bacterium Staphylococcus aureus has a strong preference for NADPH [3], while the bacterium Bacillus megaterium contains both NADH and NADPH-dependent enzymes [1].