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A flavoprotein. Not identical with EC 184.108.40.206 (cystine reductase), EC 220.127.116.11 (glutathione-disulfide reductase) or EC 18.104.22.168 (bis-gamma-glutamylcystine reductase). The enzyme from the bacterium Staphylococcus aureus has a strong preference for NADPH , while the bacterium Bacillus megaterium contains both NADH and NADPH-dependent enzymes .