1.8.1.15: mycothione reductase

This is an abbreviated version!
For detailed information about mycothione reductase, go to the full flat file.

Word Map on EC 1.8.1.15

1.8.1.15

tuberculosis

actinobacteria

glutamicum

mycoredoxin-1

dithiolic

sulfenic

antituberculosis

ms-based

subversive

natalensis

nadph-binding

antimycobacterial

monothiolic

mtahpe

euclea

isoniazid

mycothiol-dependent

peroxidatic

oxidized-reduced

medicine

molecular biology

analysis

Reaction

2 mycothiol +

Synonyms

MSH disulfide reductase, MtMtr, MTR, mycothiol disulfide reductase, mycothiol disulphide reductase, mycothiol-disulfide reductase, mycothione disulphide reductase, mycothione reductase, NADPH-dependent mycothiol reductase, NADPH-dependent mycothione reductase

ECTree

1 Oxidoreductases

1.8 Acting on a sulfur group of donors

1.8.1 With NAD⁺ or NADP⁺ as acceptor

1.8.1.15 mycothione reductase

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Results	in table
840	AA Sequence
4	Application
8	Cloned(Commentary)
17	Cofactor
1	Expression
9	General Information
3	Inhibitors
9	kcat/KM [mM/s]
1	Ki Value [mM]
35	KM Value [mM]
5	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
233	Organism
1	Pathway
3	pH Optimum
7	Protein Variants
4	Purification (Commentary)
1	Reaction
3	Reaction Type
22	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
57	Substrates and Products (Substrate)
12	Subunits
31	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
24	Turnover Number [1/s]

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Cloned on EC 1.8.1.15 - mycothione reductase

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2 entries

expressed in Escherichia coli as a His-tagged fusion protein

Mycobacterium tuberculosis

701668

expressed in Escherichia coli BL21(DE3) cells

Rhodococcus erythropolis

764678

expressed in Escherichia coli DH5alpha cells

Mycobacterium tuberculosis

764667

expression in Mycobacterium smegmatis pyrF

Mycobacterium tuberculosis

288634

functional recombinant expression of tagged enzyme

Mycobacterium tuberculosis

P9WHH3

741994

overexpression of His6-tagged enzyme from expression vector pXMJ19 in Corynebacterium glutamicum. Transfected cells show increased tolerance to reactive oxygen species induced by oxidants, bactericidal antibiotics, alkylating agents, and heavy metals

Corynebacterium glutamicum

743814