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1.8.1.6: cystine reductase

This is an abbreviated version!
For detailed information about cystine reductase, go to the full flat file.

Word Map on EC 1.8.1.6

Reaction

2 L-cysteine +

NAD+
=
L-cystine
 +
NADH
 +
H+

Synonyms

CydDC, CysR, cystine reductase (NADH), cystine reductase (NADH2), EC 1.6.4.1, L-cysteine:NAD+ oxidoreductase, L-cystine reductase, NADH-dependent cystine reductase, NADH2:L-cystine oxidoreductase, reductase, cystine, thioredoxin domain containing 17, thioredoxin-like 5, TRP14, TXNDC17, TXNL5

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.6 cystine reductase

Reference

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Reference on EC 1.8.1.6 - cystine reductase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Romano, A.H.; Nickerson, W.J.
Cystine reductase of pea seeds and yeasts
J. Biol. Chem.
208
409-416
1954
Saccharomyces cerevisiae, Candida albicans, Pisum sativum
Manually annotated by BRENDA team
Maresca, B.; Jacobson, E.; Medoff, G.; Kobayashi, G.
Cystine reductase in the dimorphic fungus Histoplasma capsulatum
J. Bacteriol.
135
987-992
1978
Histoplasma capsulatum
Manually annotated by BRENDA team
Thibert, R.J.; Sarwar, M.; Carroll, J.E.
Simultaneous determination of cysteine and cystine using N-bromosuccinimide: application in an enzymic system - cystine reductase
Mikrochim. Acta
3
615-624
1969
Saccharomyces cerevisiae
-
Manually annotated by BRENDA team
Carroll, J.E.; Kosicki, G.W.; Thibert, R.J.
alpha-Substituted cystines as possible substrates for cystine reductase and L-amino acid oxidase
Biochim. Biophys. Acta
198
601-603
1970
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Kim, S.K.; Rahman, A.; Conover, R.C.; Johnson, M.K.; Mason, J.T.; Gomes, V.; Hirasawa, M.; Moore, M.L.; Leustek, T.; Knaff, D.B.
Properties of the cysteine residues and the iron-sulfur cluster of the assimilatory 5-adenylyl sulfate reductase from Enteromorpha intestinalis
Biochemistry
45
5010-5018
2006
Ulva intestinalis
Manually annotated by BRENDA team
Ondarza, R.N.; Iturbe, A.; Hernandez, E.
The effects by neuroleptics, antimycotics and antibiotics on disulfide reducing enzymes from the human pathogens Acanthamoeba polyphaga and Naegleria fowleri
Exp. Parasitol.
115
41-47
2007
Naegleria fowleri, Acanthamoeba polyphaga
Manually annotated by BRENDA team
Pader, I.; Sengupta, R.; Cebula, M.; Xu, J.; Lundberg, J.O.; Holmgren, A.; Johansson, K.; Arner, E.S.
Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase
Proc. Natl. Acad. Sci. USA
111
6964-6969
2014
Homo sapiens (Q9BRA2), Homo sapiens
Manually annotated by BRENDA team
Mironov, A.; Seregina, T.; Shatalin, K.; Nagornykh, M.; Shakulov, R.; Nudler, E.
CydDC functions as a cytoplasmic cystine reductase to sensitize Escherichia coli to oxidative stress and aminoglycosides
Proc. Natl. Acad. Sci. USA
117
23565-23570
2020
Escherichia coli
Manually annotated by BRENDA team