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1.8.1.9: thioredoxin-disulfide reductase

This is an abbreviated version!
For detailed information about thioredoxin-disulfide reductase, go to the full flat file.

Word Map on EC 1.8.1.9

Reaction

thioredoxin
+
NADP+
=
thioredoxin disulfide
 +
NADPH
 +
H+

Synonyms

all0737, ApTR, At2g41680, AtNTRA, AtNTRB, bacillithiol disulfide reductase, bacillithiol-disulfide reductase, BBOV_I002190, Bdr, BSSB reductase, CeTR2, DmTR, DmTrxR, DmTrxR-1, EC 1.6.4.5, EhTRXR, ferredoxin:thioredoxin reductase, FTR, general stress protein 35, GSP35, HCOI_01258400, hemolysate thioredoxin reductase, hemolysate TR, hTrxR, HvNTR1, HvNTR2, L-TR, L-TrxR, More, MtNTRC, mTR3, multifunctional thioredoxin-glutathione reductase, NAD(P)H:paraquat oxidoreductase, NADP-dependent thioredoxin reductase, NADP-linked thioredoxin reductase, NADP-thioredoxin reductase, NADP-thioredoxin reductase C, NADPH thioredoxin reductase, NADPH thioredoxin reductase C, NADPH-dependent thioredoxin reductase, NADPH-dependent thioredoxin reductase 2, NADPH-dependent thioredoxin reductase C, NADPH-dependent thioredoxin reductase I, NADPH-dependent thioredoxin reductase-1, NADPH-dependent TRX reductase, NADPH-thioredoxin reductase, NADPH-thioredoxin reductase C, NADPH-Trx reductase, NADPH2:oxidized thioredoxin oxidoreductase, NAPDH-dependent BSSB reductase, NTR, Ntr1, NTR2, Ntr3, NTRA, NTRAB, NtrB, NTRC, PH0178, PH1426, PhRP, PhTrxR, protein-disulfide oxidoreductase, reductase, thioredoxin, SEP1, taTrxR, TGR, thioredoxin glutathione reductase, thioredoxin h reductase, thioredoxin reductase, thioredoxin reductase (NADPH), thioredoxin reductase 1, thioredoxin reductase 2, thioredoxin reductase-1, thioredoxin reductase1, TON_1603, TR, TR1, TR2, TR3, TRase, TrR, Trr1, Trr1p, TRR2, Trx1, Trx3, TrxB, TrxB1, TrxB2, TrxR, TrxR-1(cyto), TrxR-1(mito), TrxR1, TrxR2, TrxR3, TrxRB3, TRXRD, TrxRh1, TrxRh2, TrxT, Txnrd1, TXNRD1-v3, Txnrd2, TXNRD3, TxrR-1, YpdA

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.9 thioredoxin-disulfide reductase

Cloned

Cloned on EC 1.8.1.9 - thioredoxin-disulfide reductase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
amino acid and DNA sequence analysis
-
cloned into pET28a, resulting in a cleavable N-terminal 6xHis-tagged fusion protein. Protein was produced in BL21pRIL Escherichia coli
expressed in Escherichia coli
expressed in Escherichia coli BL21 (pLysS) cells
expressed in Escherichia coli BL21 pLysS cells
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3) or ER2566 cells
-
expressed in Escherichia coli BL21(DE3)pLysS cells
expressed in Escherichia coli ER2566 cells
expressed in Escherichia coli Rosetta (DE3) cells
expressed in Escherichia coli strain DH5alpha
-
expressed in Escherichia coli strain NovaBlue
-
expressed in Escherichia coli strains W3110 and K1380
-
expressed in Escherichia coli XL1-Blue cells
expression in Escherichia coli
expression in Escherichia coli as a His-tagged protein
expression in Escherichia coli BL21
expression in Escherichia coli Rosetta(DE3)
expression in Escherichia coli with an amino-terminal hexa-His-tag for purification
expression of cytosolic and mitochondrial isoform as His-tagged enzymes in Escherichia coli
-
expression of hemagglutinin-tagged TrxRh1 in transfected Trichomonas vaginalis cells reveales that its N-terminal extension is necessary to import the protein into the organelles
-
expression of His-tagged or Strep-tagged wild-type and mutants in Escherichia coli, DNA sequence analysis
-
expression of NTRC enzyme tagged at the C-terminus with nine copies of the myc epitope (9×myc), six histidine residues (6×His), a 3C protease cleavage site (3C), and two copies of the protein A IgG-binding domain
expression of wild-type and mutants in Escherichia coli
-
expression of wild-type as His-tagged protein and mutant C53S in Escherichia coli, DNA sequence analysis
expression of wild-type fusion protein and truncated mutant
-
gene ypdA, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21
gene ypdA, recombinant overexpression of His-tagged enzyme in Escherichia coli strain BL21(DE3)
HEK-293 cells overexpressing TrxR2 are more resistant to impairment of complex III bypassing function of TrxR2
nucleotide sequence analysis and comparison
overexpression of antisense mutant in Escherichia coli, expression of wild-type in COS-7 cells, amino acid sequence analysis
-
overexpression of wild-type and mutant enzymes from plasmids
-
overproduction of thioredoxin reductase in Lactobacillus plantarum WCFS1 improves the tolerance of the strain towards an oxidative stress produced by hydrogen peroxide or diamide
-
recombinant protein carrying an amino terminal His6-tag is produced in Escherichia coli
-
recombinant protein carrying an aminoterminal His6-tag is produced in Escherichia coli
-
strong overexpression in Escherichia coli, DNA sequence analysis
-
subunit complex of enzyme via C135 with thioredoxin C32, mutant complex S135-S32, expression from plasmid
-
the full-length Sec489Cys mutant as well as the truncated mTR3 missing the C-terminal CUG tripeptide sequence is expressed as a TR-intein-chitin binding domain fusion protein in Escherichia coli
the internal conservative sequence of TrxR1 is cloned into the pMD18-T vector
truncated form of thioredoxin reductase (missing the C-terminal eight amino acids-TRtrunc), is produced by amplifying the coding region
-
trxB gene, cloning of active site mutants, expression from plasmids
-
trxB gene, DNA sequence analysis
-
wild-type and C-terminal variants
-