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1.8.1.9: thioredoxin-disulfide reductase

This is an abbreviated version!
For detailed information about thioredoxin-disulfide reductase, go to the full flat file.

Word Map on EC 1.8.1.9

Reaction

thioredoxin
+
NADP+
=
thioredoxin disulfide
+
NADPH
+
H+

Synonyms

all0737, ApTR, At2g41680, AtNTRA, AtNTRB, bacillithiol disulfide reductase, bacillithiol-disulfide reductase, BBOV_I002190, Bdr, BSSB reductase, CeTR2, DmTR, DmTrxR, DmTrxR-1, EC 1.6.4.5, EhTRXR, ferredoxin:thioredoxin reductase, FTR, general stress protein 35, GSP35, HCOI_01258400, hemolysate thioredoxin reductase, hemolysate TR, hTrxR, HvNTR1, HvNTR2, L-TR, L-TrxR, More, MtNTRC, mTR3, multifunctional thioredoxin-glutathione reductase, NAD(P)H:paraquat oxidoreductase, NADP-dependent thioredoxin reductase, NADP-linked thioredoxin reductase, NADP-thioredoxin reductase, NADP-thioredoxin reductase C, NADPH thioredoxin reductase, NADPH thioredoxin reductase C, NADPH-dependent thioredoxin reductase, NADPH-dependent thioredoxin reductase 2, NADPH-dependent thioredoxin reductase C, NADPH-dependent thioredoxin reductase I, NADPH-dependent thioredoxin reductase-1, NADPH-dependent TRX reductase, NADPH-thioredoxin reductase, NADPH-thioredoxin reductase C, NADPH-Trx reductase, NADPH2:oxidized thioredoxin oxidoreductase, NAPDH-dependent BSSB reductase, NTR, Ntr1, NTR2, Ntr3, NTRA, NTRAB, NtrB, NTRC, PH0178, PH1426, PhRP, PhTrxR, protein-disulfide oxidoreductase, reductase, thioredoxin, SEP1, taTrxR, TGR, thioredoxin glutathione reductase, thioredoxin h reductase, thioredoxin reductase, thioredoxin reductase (NADPH), thioredoxin reductase 1, thioredoxin reductase 2, thioredoxin reductase-1, thioredoxin reductase1, TON_1603, TR, TR1, TR2, TR3, TRase, TrR, Trr1, Trr1p, TRR2, Trx1, Trx3, TrxB, TrxB1, TrxB2, TrxR, TrxR-1(cyto), TrxR-1(mito), TrxR1, TrxR2, TrxR3, TrxRB3, TRXRD, TrxRh1, TrxRh2, TrxT, Txnrd1, TXNRD1-v3, Txnrd2, TXNRD3, TxrR-1, YpdA

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.9 thioredoxin-disulfide reductase

Turnover Number

Turnover Number on EC 1.8.1.9 - thioredoxin-disulfide reductase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.88 - 87.8
5,5'-dithio-bis(2-nitrobenzoic acid)
0.012 - 106.3
5,5'-dithiobis(2-nitrobenzoic acid)
24.1 - 174.3
5-hydroxy-1,4-naphthoquinone
167
alloxan
-
-
3.9 - 15.3
Arabidopsis thaliana thioredoxin 3
-
20
Babesia bovis thioredoxin
pH 8.0, 30°C
-
0.16 - 66.7
DTNB
11.7
ebsulfur
-
pH 7.5, temperature not specified in the publication
1.7
ebsulfur disulfide
-
pH 7.5, temperature not specified in the publication
4.1 - 9.4
Escherichia coli thioredoxin
-
8
glutaredoxin 4
-
-
-
5.1
GSSG
-
-
12.1
Hordeum vulgare thioredoxin 1
wild-type, pH 7.5, temperature not specified in the publication
-
1.8 - 11.4
Hordeum vulgare thioredoxin 2
-
2.6 - 5.3
Hordeum vulgare thioredoxin 2 mutant E86A
-
7.9
Hordeum vulgare thioredoxin 2 mutant G57P
wild-type, pH 7.5, temperature not specified in the publication
-
15.9
Hordeum vulgare thioredoxin 2 mutant I51G
wild-type, pH 7.5, temperature not specified in the publication
-
2.25 - 3.26
Hordeum vulgare thioredoxin disulfide h1
-
0.43 - 2.98
Hordeum vulgare thioredoxin disulfide h2
-
1.183 - 6.08
hydrogen peroxide
1.6 - 31.2
Lipoamide
1.8
lipoic acid
-
isoform TrxR1, in 50 mM Tris-HCl, 1 mM EDTA, pH 8.0, at 37°C
16.05
methaneseleninic acid
-
at pH 6.1 and 37°C
12 - 31
methylseleninate
0.06 - 0.817
NADH
0.25 - 109.8
NADPH
500
protein disulfide-isomerase
-
-
-
1.83
rat thioredoxin
-
insulin coupled assay
-
1600
selenocysteine
-
-
0.016 - 1300
thioredoxin
43.7
thioredoxin 1
-
wild type enzyme, pH and temperature not specified in the publication
42.9 - 47.1
thioredoxin 2
-
34
thioredoxin 3
-
wild type enzyme, pH and temperature not specified in the publication
-
2 - 2.2
thioredoxin 41
-
2.6 - 2.7
thioredoxin 8
-
0.083 - 114.1
thioredoxin disulfide
2.2
thioredoxin disulfide 41
-
pH 7, 30°C
-
1.43
thioredoxin disulfide 8
-
pH 7, 30°C
-
22.7
thioredoxin K36E, thioredoxin P34S
-
mutant, pH 8.0
-
10.3
thioredoxin-CAC, thioredoxin-R
-
mutant, pH 8.0
-
additional information
additional information
-