1.8.3.7: formylglycine-generating enzyme

This is an abbreviated version!
For detailed information about formylglycine-generating enzyme, go to the full flat file.

Word Map on EC 1.8.3.7

1.8.3.7

sulfatases

metachromatic

mucopolysaccharidosis

leukodystrophy

ichthyosis

antibody-drug

ultra-rare

morquio

medicine

Reaction

+ 2 a thiol =

Synonyms

AtsB, C-alpha-formylglycine-generating enzyme 1, Calpha-formylglycine-generating enzyme, Calpha-formylglycine-generating enzyme 1, FGE, FGly-generating enzyme, formylglycine generating enzyme, sulfatase-modifying factor 1, SUMF1

ECTree

1 Oxidoreductases

1.8 Acting on a sulfur group of donors

1.8.3 With oxygen as acceptor

1.8.3.7 formylglycine-generating enzyme

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Results	in table
4	Activating Compound
64	AA Sequence
9	Application
16	Cloned(Commentary)
2	Cofactor
9	Crystallization (Commentary)
188	Disease/ Diagnostics
1	Expression
8	General Information
1	IC50 Value
6	Inhibitors
20	kcat/KM [mM/s]
14	KM Value [mM]
12	Localization
19	Metals/Ions
17	Natural Substrates/ Products (Substrates)
243	Organism
14	PDB ID
1	pH Optimum
1	pH Range
2	Posttranslational Modification
66	Protein Variants
12	Purification (Commentary)
1	Reaction
49	Reference
14	Source Tissue
54	Substrates and Products (Substrate)
7	Subunits
70	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Temperature Stability [°C]
17	Turnover Number [1/s]

Purification

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Purification on EC 1.8.3.7 - formylglycine-generating enzyme

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4 entries

amylose resin column chromatography

Streptomyces coelicolor

742835

HisTrap column chromatography

Mycobacterium tuberculosis

742835

HisTrap column chromatography and Superdex 200 gel filtration

Homo sapiens

Q8NBK3

742496

HisTrap column chromatography, and Superdex 200 gel filtration

Homo sapiens

Q8NBK3

742435

HisTrap Excel resin column chromatography and Sephadex G-25 gel filtration

Homo sapiens

Q8NBK3

742873

MonoQ column chromatography

Homo sapiens

Q8NBK3

742630

Ni-NTA column chromatography and Sephadex G-25 gel filtration

Streptomyces coelicolor

Q9F3C7

742873

Ni-NTA column chromatography, Talon metal affinity resin column chromatography, and Sephadex G-25 gel filtration

Klebsiella pneumoniae

741881