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1.8.3.7: formylglycine-generating enzyme

This is an abbreviated version!
For detailed information about formylglycine-generating enzyme, go to the full flat file.

Word Map on EC 1.8.3.7

Reaction

a [sulfatase]-L-cysteine
+
O2
 + 2 a thiol =
a [sulfatase]-3-oxo-L-alanine
 +
hydrogen sulfide
 +
a disulfide
 +
H2O

Synonyms

AtsB, C-alpha-formylglycine-generating enzyme 1, Calpha-formylglycine-generating enzyme, Calpha-formylglycine-generating enzyme 1, FGE, FGly-generating enzyme, formylglycine generating enzyme, sulfatase-modifying factor 1, SUMF1

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.3 With oxygen as acceptor
                1.8.3.7 formylglycine-generating enzyme

Sequence

topprint

Sequence on EC 1.8.3.7 - formylglycine-generating enzyme

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
FGE_MYCTU
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
299
0
32744
Swiss-Prot
-
FGE_STRCO
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
314
0
33736
Swiss-Prot
-
FGE_THECD
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9)
303
0
33276
Swiss-Prot
-
SUMF1_BOVIN
374
1
40342
Swiss-Prot
Secretory Pathway (Reliability: 2)
SUMF1_HUMAN
374
0
40556
Swiss-Prot
Secretory Pathway (Reliability: 2)
SUMF1_MOUSE
372
0
40659
Swiss-Prot
Secretory Pathway (Reliability: 2)
A0A6S7EVX4_9BURK
377
1
41193
TrEMBL
-
A0A6S7ARB6_9BURK
382
1
42042
TrEMBL
-
Q1PZW3_KUEST
263
1
31164
TrEMBL
-
A0A6N8HLK4_9BACI
271
0
30704
TrEMBL
-
A0A6J8DAQ6_MYTCO
376
0
43220
TrEMBL
Secretory Pathway (Reliability: 3)
A0A7R6WBI9_9GAMM
Methyloprofundus sp
269
0
30872
TrEMBL
-
A0A7R6WBW7_9GAMM
Methyloprofundus sp
282
0
31758
TrEMBL
-
A0A653T7N3_9MICC
333
0
36348
TrEMBL
-
A0A6J4GMU4_9FLAO
377
1
41638
TrEMBL
-
A0A6S6Z286_9BURK
337
1
38311
TrEMBL
-
A0A7U7ENY1_9PSED
235
0
26612
TrEMBL
-
A0A653MH25_9MICC
311
0
34813
TrEMBL
-
A0A6G8NPR6_9BURK
266
0
29646
TrEMBL
-
A0A6S6YRJ7_9BURK
382
1
41885
TrEMBL
-
A0A653J6B3_9SPHN
325
0
36223
TrEMBL
-
A0A7J5WZC7_9ACTN
268
0
29016
TrEMBL
-
A0A653XX89_9SPHN
306
0
33314
TrEMBL
-
A0A7R8CVE6_LEPSM
268
0
30443
TrEMBL
other Location (Reliability: 1)
A0A5P9Q8J8_9MICO
295
0
32199
TrEMBL
-
A0A6S7EY92_9BURK
330
0
37132
TrEMBL
-
A0A6S7CEK5_9BURK
387
1
42421
TrEMBL
-
A0A7T6XBN4_RALPI
263
0
28666
TrEMBL
-
A0A7G2CXL7_9MICO
297
0
32936
TrEMBL
-
A0A6S7DYL6_9BURK
381
1
41554
TrEMBL
-
A0A812E2P6_SEPPH
375
1
42807
TrEMBL
Secretory Pathway (Reliability: 2)
A0A7R6WD97_9GAMM
Methyloprofundus sp
863
0
97994
TrEMBL
-
A0A6S6Z9W4_9BURK
345
0
38854
TrEMBL
-
A0A418SLA5_9RHOB
296
0
32766
TrEMBL
-
A0A7R7AIQ4_9GAMM
Methyloprofundus sp
979
0
112195
TrEMBL
-
A0A822IDS9_9EURY
1107
0
126857
TrEMBL
-
A0A654BUM6_SPHMU
345
0
38893
TrEMBL
-
A0A811GS50_9BURK
333
0
37268
TrEMBL
-
A0A653N516_9BURK
377
1
41133
TrEMBL
-
A0A653I928_9BURK
271
0
29641
TrEMBL
-
A0A6S7E197_9BURK
330
0
37121
TrEMBL
-
A0A6J4GM40_9FLAO
377
1
41704
TrEMBL
-
A0A6S6ZRH4_9BURK
380
1
41622
TrEMBL
-
A0A6S7A7M5_9BURK
333
0
37231
TrEMBL
-
A0A653LNF9_9FLAO
377
0
41915
TrEMBL
-
A0A7R6WBU1_9GAMM
Methyloprofundus sp
279
0
31327
TrEMBL
-
A0A6S6ZBT8_9BURK
388
1
42521
TrEMBL
-
A0A6S7AWY3_9BURK
333
0
37992
TrEMBL
-
A0A508X0Z4_9HYPH
319
0
35550
TrEMBL
-
A0A6J5D509_9BURK
323
0
35279
TrEMBL
-
A0A6J5D389_9BURK
349
1
37623
TrEMBL
-
A0A6S7BYE4_9BURK
355
0
39831
TrEMBL
-
A0A811GU56_9BURK
380
1
41880
TrEMBL
-
A0A6S7F0W0_9BURK
360
0
38759
TrEMBL
-
A0A6S7BP01_9BURK
400
1
43905
TrEMBL
-
A0A6J5A392_9BURK
328
0
36660
TrEMBL
-
A0A7R6WA58_9GAMM
Methyloprofundus sp
818
0
90776
TrEMBL
-
A0A653JHE9_9BURK
331
0
35317
TrEMBL
-
A0A6J5GJS6_9BURK
327
0
36536
TrEMBL
-
A0A2M9H2P9_9BURK
331
0
37062
TrEMBL
-
A0A6S7CJL8_9BURK
328
0
36673
TrEMBL
-
A0A7U7EQS6_9PSED
334
0
36989
TrEMBL
-
A0A654DY88_9BACT
341
0
38384
TrEMBL
-
D1ADF2_THECD
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9)
461
0
51897
TrEMBL
-