1.8.4.4: glutathione-cystine transhydrogenase

This is an abbreviated version!
For detailed information about glutathione-cystine transhydrogenase, go to the full flat file.

Reaction

2 glutathione +

cystine
=
glutathione disulfide
+ 2 cysteine

Synonyms

GSH-cystine transhydrogenase, NADPH-dependent GSH-cystine transhydrogenase, transhydrogenase, glutathione-cystine

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.4 With a disulfide as acceptor
                1.8.4.4 glutathione-cystine transhydrogenase

General Stability

General Stability on EC 1.8.4.4 - glutathione-cystine transhydrogenase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
ammonium sulfate, 1 M, complete stabilization, 6 days at 20°C
-
cystine, alone: no stabilization, in addition to glutathione: increases stabilizing effect
-
EDTA stabilizes
-
ethylene glycol, 10%, stabilizes
-
glutathione stabilizes, stabilizing effect increased by cystine
-
glycerol, no stabilization
-