1.8.4.4: glutathione-cystine transhydrogenase

This is an abbreviated version!
For detailed information about glutathione-cystine transhydrogenase, go to the full flat file.

Reaction

2 glutathione +

cystine
=
glutathione disulfide
+ 2 cysteine

Synonyms

GSH-cystine transhydrogenase, NADPH-dependent GSH-cystine transhydrogenase, transhydrogenase, glutathione-cystine

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.4 With a disulfide as acceptor
                1.8.4.4 glutathione-cystine transhydrogenase

Substrates Products

Substrates Products on EC 1.8.4.4 - glutathione-cystine transhydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
beta-hydroxyethyl disulfide + GSH
?
show the reaction diagram
-
-
-
0
?
cystine + GSH
cysteine + GSSG
show the reaction diagram
D-cystine + 2 GSH
2 D-cysteine + GSSG
show the reaction diagram
-
-
-
0
?
diacetyl-L-cystine + GSH
?
show the reaction diagram
-
-
-
0
?
dimethyl disulfide + GSH
?
show the reaction diagram
-
-
-
0
?
dithiodiglycolic acid + GSH
?
show the reaction diagram
-
-
-
0
?
GSSG + GSH
GSSG + GSH
show the reaction diagram
-
-
-
0
?
homocystine + GSH
?
show the reaction diagram
-
-
-
0
?
L-cystine + GSH
L-cysteine + GSSG
show the reaction diagram
-
-
-
0
?
L-cystine diamide + GSH
?
show the reaction diagram
-
-
-
0
?
L-cystinyldiglycine + GSH
L-Cys-Gly-Gly + GSSG
show the reaction diagram
-
-
-
0
?
lipoic acid oxidized + GSH
?
show the reaction diagram
-
-
-
0
?
additional information
?
-