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1.8.5.8: eukaryotic sulfide quinone oxidoreductase

This is an abbreviated version!
For detailed information about eukaryotic sulfide quinone oxidoreductase, go to the full flat file.

Reaction

hydrogen sulfide
+
glutathione
+
a quinone
=
S-sulfanylglutathione
+
a quinol

Synonyms

glutathione:CoQ reductase, HMT2, ScSQR, SQOR, SQR, Sqrdl, sulfide : quinone oxidoreductase, sulfide quinone oxidoreductase, sulfide:quinone oxidoreductase

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.5 With a quinone or similar compound as acceptor
                1.8.5.8 eukaryotic sulfide quinone oxidoreductase

IC50 Value

IC50 Value on EC 1.8.5.8 - eukaryotic sulfide quinone oxidoreductase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0000094
2-ethoxy-4-(4-fluorophenyl)-5H-indeno[1,2-b]pyridine-3-carbonitrile
Homo sapiens
pH and temperature not specified in the publication
-
0.000021
2-methoxy-4-phenyl-5H-indeno[1,2-b]pyridine-3-carbonitrile
Homo sapiens
pH and temperature not specified in the publication
-
0.00034
4-(2-chlorophenyl)-2-methoxy-5H-indeno[1,2-b]pyridine-3-carbonitrile
Homo sapiens
pH and temperature not specified in the publication
-
0.000029
4-(4-aminophenyl)-6-methoxy-3'-methyl[2,2'-bipyridine]-5-carbonitrile
Homo sapiens
pH and temperature not specified in the publication
-
0.00003
ethyl [(3-cyano-4,6-diphenylpyridin-2-yl)oxy]acetate
Homo sapiens
pH and temperature not specified in the publication
-