1.8.98.5: H2:CoB-CoM heterodisulfide,ferredoxin reductase

This is an abbreviated version!
For detailed information about H2:CoB-CoM heterodisulfide,ferredoxin reductase, go to the full flat file.

Reaction

2 reduced ferredoxin [iron-sulfur] cluster +

Synonyms

CoB-CoM heterodisulfide reductase, F420-non-reducing hydrogenase, H2-driven FBEB, H2: CoM-S-S-CoB oxidoreductase, H2: heterodisulfide oxidoreductase complex, HdrA, hdrA1B1C1, HdrABC, HdrABC-MvhAGD, HdrB, HdrC, HdrDE, HdrDE-VhoGAC, heterodisulfide reductase, heterodisulfide reductase complex, hydrogenase, More, Mvh, MvhA, MvhADG, MvhADG/HdrABC, MvhD, MvhG, VhoGAC, Vhu

ECTree

     1 Oxidoreductases

         1.8 Acting on a sulfur group of donors

             1.8.98 With other, known, physiological acceptors

                1.8.98.5 H2:CoB-CoM heterodisulfide,ferredoxin reductase

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Results	in table
7	Activating Compound
62	AA Sequence
1	Cloned(Commentary)
31	Cofactor
1	Crystallization (Commentary)
68	General Information
2	Inhibitors
6	Localization
5	Metals/Ions
1	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
48	Organism
6	Pathway
5	pH Optimum
1	pH Range
4	Purification (Commentary)
19	Reaction
41	Reference
6	Source Tissue
5	Specific Activity [micromol/min/mg]
71	Substrates and Products (Substrate)
16	Subunits
84	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.8.98.5 - H2:CoB-CoM heterodisulfide,ferredoxin reductase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

11 entries

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

18 entries

H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+

4 entries

reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+

H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 entries

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanococcus maripaludis

-

-

764153

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanococcus maripaludis LL

-

-

764153

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermobacter marburgensis

Q50756; Q50755; Q50754; P60227; P60239; P60238

-

764200

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermobacter marburgensis ATCC BAA-927

Q50756; Q50755; Q50754; P60227; P60239; P60238

-

764200

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermobacter marburgensis DSM 2133

Q50756; Q50755; Q50754; P60227; P60239; P60238

-

764200

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermobacter marburgensis JCM 14651

Q50756; Q50755; Q50754; P60227; P60239; P60238

-

764200

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermobacter marburgensis Marburg

Q50756; Q50755; Q50754; P60227; P60239; P60238

-

764200

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermobacter marburgensis NBRC 100331

Q50756; Q50755; Q50754; P60227; P60239; P60238

-

764200

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermobacter marburgensis OCM 82

Q50756; Q50755; Q50754; P60227; P60239; P60238

-

764200

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermobacter wolfeii

-

-

764200

-

-

?

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

Methanothermococcus thermolithotrophicus

A0A2D0TCB9; A0A2D0TCB4; A0A2D0TC97; A0A2D0TCA6; A0A2D0TC99; A0A2D0TC98

-

764200

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanocella conradii

-

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanococcus maripaludis

Q6LWL2; Q6LY38; Q6LYD8; Q6LY39; Q6LYD7

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanococcus maripaludis LL

Q6LWL2; Q6LY38; Q6LYD8; Q6LY39; Q6LYD7

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanonatronarchaeum thermophilum

A0A1Y3GAE7

-

764660

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanonatronarchaeum thermophilum AMET1

A0A1Y3GAE7

-

764660

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanosarcina acetivorans

-

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanosarcina barkeri

-

-

764762

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanosarcina barkeri DSM 800

-

-

764762

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanosarcina barkeri MS

-

-

764762

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanosarcina barkeri MS DSM 800

-

-

764762

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis

Q50756; Q50755; Q50754

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis ATCC BAA-927

Q50756; Q50755; Q50754

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis DSM 2133

Q50756; Q50755; Q50754

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis JCM 14651

Q50756; Q50755; Q50754

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis Marburg

Q50756; Q50755; Q50754

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis NBRC 100331

Q50756; Q50755; Q50754

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis OCM 82

Q50756; Q50755; Q50754

-

764753

-

-

?

2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+

2 H2 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermococcus thermolithotrophicus

-

-

764753

-

-

?

H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+

Methanobacterium thermoautotrophicus

-

-

744833

-

-

?

H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+

Methanobacterium thermoautotrophicus DSM 2133

-

-

744833

-

-

?

H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+

Methanothermobacter marburgensis

-

-

744179

-

-

?

H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+

Methanothermobacter marburgensis DSM 2133

-

-

744179

-

-

?

reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+

H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis

-

-

746286

-

-

?

reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+

H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB

Methanothermobacter marburgensis DSM 2133

-

-

746286

-

-

?