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EC 2.6.99.4 Details

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EC number

2.6.99.4

Accepted name

N⁶-L-threonylcarbamoyladenine synthase

Reaction

L-threonylcarbamoyladenylate + adenine³⁷ in tRNA = AMP + N⁶-L-threonylcarbamoyladenine³⁷ in tRNA

Other name(s)

t6A synthase, Kae1, ygjD (gene name), Qri7

Systematic name

L-threonylcarbamoyladenylate:adenine³⁷ in tRNA N⁶-L-threonylcarbamoyltransferase

Comment

The enzyme is involved in the synthesis of N⁶-threonylcarbamoyladenosine³⁷ in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNA^Ile, tRNA^Thr, tRNA^Asn, tRNA^Lys, tRNA^Ser and tRNA^Arg [3].

History

created 2014, deleted 2014

EC Tree

1 Oxidoreductases

2 Transferases

2.1 Transferring one-carbon groups

2.2 Transferring aldehyde or ketonic groups

2.2.1 Transketolases and transaldolases

2.3 Acyltransferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.2 Pentosyltransferases

2.4.3 Sialyltransferases

2.4.99 Transferring other glycosyl groups

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.2 Amidinotransferases (deleted sub-subclass)

2.6.3 Oximinotransferases

2.6.99 Transferring other nitrogenous groups

2.6.99.1 dATP(dGTP)—DNA purinetransferase

2.6.99.2 pyridoxine 5′-phosphate synthase

2.6.99.3 O-ureido-L-serine synthase

2.6.99.4 N⁶-L-threonylcarbamoyladenine synthase

2.7 Transferring phosphorus-containing groups

2.8 Transferring sulfur-containing groups

2.9 Transferring selenium-containing groups

2.9.1 Selenotransferases

2.10 Transferring molybdenum- or tungsten-containing groups

2.10.1 Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors

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Release 2023.1 (January 2023)