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EC 2.5.1.30 Details
EC number
2.5.1.30
Accepted name
heptaprenyl diphosphate synthase
Reaction
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate
Other name(s)
all-trans-heptaprenyl-diphosphate synthase, heptaprenyl pyrophosphate synthase, heptaprenyl pyrophosphate synthetase, HepPP synthase, HepPS, heptaprenylpyrophosphate synthetase
Systematic name
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 4 isopentenyl units)
CAS registry number
74506-59-5
Comment
This enzyme catalyses the condensation reactions resulting in the formation of all-trans-heptaprenyl diphosphate, the isoprenoid side chain of ubiquinone-7 and menaquinone-7. The enzyme adds four isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry.
History
created 1984, modified 2010
EC Tree
2.5.1.12 created 1972, deleted 1976
2.5.1.13 created 1972, deleted 1976
2.5.1.14 created 1972, deleted 1976
2.5.1.37 created 1989, deleted 2004
2.5.1.40 created 1992, deleted 1999