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EC 1.14.14.85 Details
EC number
1.14.14.85
Accepted name
7-deoxyloganate 7-hydroxylase
Reaction
7-deoxyloganate + [reduced NADPH—hemoprotein reductase] + O2 = loganate + [oxidized NADPH—hemoprotein reductase] + H2O
Other name(s)
CYP72A224 (gene name), 7-deoxyloganin 7-hydroxylase (incorrect), 7-deoxyloganin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (7α-hydroxylating) (incorrect)
Systematic name
7-deoxyloganate,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (7α-hydroxylating)
CAS registry number
335305-40-3
Comment
The enzyme, characterized from the plant Catharanthus roseus, is a cytochrome P-450 (heme-thiolate) enzyme. It catalyses a reaction in the pathway leading to biosynthesis of monoterpenoid indole alkaloids.
History
created 2002 as EC 1.14.13.74, transferred 2018 to EC 1.14.14.85, modified 2018
EC Tree
2.5.1.12 created 1972, deleted 1976
2.5.1.13 created 1972, deleted 1976
2.5.1.14 created 1972, deleted 1976
2.5.1.37 created 1989, deleted 2004
2.5.1.40 created 1992, deleted 1999