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EC 3.1.3.80 Details
EC number
3.1.3.80
Accepted name
2,3-bisphosphoglycerate 3-phosphatase
Reaction
2,3-bisphospho-D-glycerate + H2O = 2-phospho-D-glycerate + phosphate
Other name(s)
MIPP1, 2,3-BPG 3-phosphatase
Systematic name
2,3-bisphospho-D-glycerate 3-phosphohydrolase
Comment
This reaction is a shortcut in the Rapoport-Luebering shunt. It bypasses the reactions of EC 5.4.2.11/EC 5.4.2.12 [phosphoglycerate mutases (2,3-diphosphoglycerate-dependent and independent)] and directly forms 2-phospho-D-glycerate by removing the 3-phospho-group of 2,3-diphospho-D-glycerate [1]. The MIPP1 protein also catalyses the reaction of EC 3.1.3.62 (multiple inositol-polyphosphate phosphatase).
History
created 2010
EC Tree
2.5.1.12 created 1972, deleted 1976
2.5.1.13 created 1972, deleted 1976
2.5.1.14 created 1972, deleted 1976
2.5.1.37 created 1989, deleted 2004
2.5.1.40 created 1992, deleted 1999