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EC Explorer

EC 1.14.13.190 Details
EC number
1.14.13.190
Accepted name
ferruginol synthase
Reaction
abieta-8,11,13-triene + NADPH + H+ + O2 = ferruginol + NADP+ + H2O
Other name(s)
miltiradiene oxidase (incorrect), CYP76AH1, miltiradiene,NADPH:oxygen oxidoreductase (ferruginol forming) (incorrect)
Systematic name
miltiradiene,NADPH:oxygen oxidoreductase (ferruginol-forming)
Comment
The enzyme is found in some members of the Lamiaceae (mint family). The enzyme from Rosmarinus officinalis (rosemary) is involved in biosynthesis of carnosic acid, while the enzyme from the Chinese medicinal herb Salvia miltiorrhiza is involved in the biosynthesis of the tanshinones, abietane-type norditerpenoid naphthoquinones that are the main lipophilic bioactive components found in the plant.
History
created 2014, modified 2015, deleted 2020
EC Tree
2.5.1.12 created 1972, deleted 1976
2.5.1.13 created 1972, deleted 1976
2.5.1.14 created 1972, deleted 1976
2.5.1.37 created 1989, deleted 2004
2.5.1.40 created 1992, deleted 1999