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EC 2.5.1.85 Details
EC number
2.5.1.85
Accepted name
all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
Reaction
geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate
Other name(s)
nonaprenyl diphosphate synthase (ambiguous), solanesyl diphosphate synthase (ambiguous), At-SPS2, At-SPS1, SPS1, SPS2
Systematic name
geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 5 isopentenyl units)
Comment
Geranylgeranyl diphosphate is preferred over farnesyl diphosphate as allylic substrate [1]. The plant Arabidopsis thaliana has two different enzymes that catalyse this reaction. SPS1 contributes to the biosynthesis of the ubiquinone side-chain while SPS2 supplies the precursor of the plastoquinone side-chains [2].
History
created 1972 as EC 2.5.1.11, part transferred 2010 to EC 2.5.1.85
EC Tree
2.5.1.12 created 1972, deleted 1976
2.5.1.13 created 1972, deleted 1976
2.5.1.14 created 1972, deleted 1976
2.5.1.37 created 1989, deleted 2004
2.5.1.40 created 1992, deleted 1999