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EC Details
EC number
Accepted name
pyridoxine 5′-phosphate synthase
1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = pyridoxine 5′-phosphate + phosphate + 2 H2O
Other name(s)
pyridoxine 5-phosphate phospho lyase, PNP synthase, PdxJ
Systematic name
1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing)
CAS registry number
In Escherichia coli, the coenzyme pyridoxal 5′-phosphate is synthesized de novo by a pathway that involves EC (erythrose-4-phosphate dehydrogenase), EC (4-phosphoerythronate dehydrogenase), EC (phosphoserine transaminase), EC (4-hydroxythreonine-4-phosphate dehydrogenase), EC (pyridoxine 5′-phosphate synthase) and EC (with pyridoxine 5′-phosphate as substrate). 1-Deoxy-D-xylulose cannot replace 1-deoxy-D-xylulose 5-phosphate as a substrate [3].
created 2006