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EC 2.6.99.1 Details
EC number
2.6.99.1
Accepted name
dATP(dGTP)—DNA purinetransferase
Reaction
(1) dATP + depurinated DNA = deoxyribose triphosphate + DNA;; (2) dGTP + depurinated DNA = deoxyribose triphosphate + DNA
Systematic name
dATP(dGTP):depurinated-DNA purine transferase
Comment
The purine residue is transferred on to the apurinic site forming a normal glycosylic bond. dATP reacts at sites of the double-stranded depurinated DNA that lack adenine, and dGTP at sites that lack guanine.
History
created 1984
EC Tree
2.6.2.1 created 1961, deleted 1965