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EC 2.8.2.32 Details
EC number
2.8.2.32
Accepted name
scymnol sulfotransferase
Reaction
3′-phosphoadenylyl sulfate + 5β-scymnol = adenosine 3′,5′-bisphosphate + 5β-scymnol sulfate
Other name(s)
3′-phosphoadenylyl sulfate:5β-scymnol sulfotransferase
Systematic name
3′-phosphoadenylyl sulfate:5β-scymnol sulfonotransferase
CAS registry number
220581-70-4
Comment
The enzyme from the shark Heterodontus portusjacksoni is able to sulfate the C27 bile salts 5β-scymnol (the natural bile salt) and 5α-cyprinol (the carp bile salt). Enzyme activity is activated by Mg2+ but inhibited by the product 5β-scymnol sulfate.
History
created 2005
EC Tree
2.8.3.4 created 1961, deleted 1964