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EC 2.8.1.5 Details
EC number
2.8.1.5
Accepted name
thiosulfate—dithiol sulfurtransferase
Reaction
thiosulfate + dithioerythritol = sulfite + 4,5-cis-dihydroxy-1,2-dithiacyclohexane (i.e. oxidized dithioerythritol) + sulfide
Other name(s)
thiosulfate reductase, TSR
Systematic name
thiosulfate:dithioerythritol sulfurtransferase
CAS registry number
9059-49-8
Comment
The enzyme from Chlorella shows very little activity towards monothiols such as glutathione and cysteine (cf. EC 2.8.1.3 thiosulfate—thiolsulfurtransferase). The enzyme probably transfers the sulfur atom onto one thiol group to form -S-S-, and sulfide is spontaneously expelled from this by reaction with the other thiol group. May be identical with EC 2.8.1.1 thiosulfate sulfurtransferase.
History
created 1989, modified 1999
EC Tree
2.8.2.12 created 1972, deleted 2001
2.8.3.4 created 1961, deleted 1964