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EC 2.8.2.34 Details

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EC number

2.8.2.34

Accepted name

glycochenodeoxycholate sulfotransferase

Reaction

3′-phosphoadenylyl sulfate + glycochenodeoxycholate = adenosine 3′,5′-bisphosphate + glycochenodeoxycholate 7-sulfate

Other name(s)

bile acid:3′-phosphoadenosine-5′-phosphosulfate sulfotransferase, bile acid:PAPS:sulfotransferase, BAST, 3′-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase

Systematic name

3′-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfonotransferase

CAS registry number

72668-90-7

Comment

The enzyme specifically sulfates glycochenodeoxycholate at the 7α-position (see also EC 2.8.2.14 bile-salt sulfotransferase). The monohydroxy bile acids glycolithocholate, chenodeoxycholate and ursodeoxycholate act as inhibitors.

History

created 2005

EC Tree

1 Oxidoreductases

2.1 Transferring one-carbon groups

2.2 Transferring aldehyde or ketonic groups

2.3 Acyltransferases

2.4 Glycosyltransferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.6 Transferring nitrogenous groups

2.7 Transferring phosphorus-containing groups

2.8 Transferring sulfur-containing groups

2.8.1 Sulfurtransferases

2.8.2 Sulfotransferases

2.8.2.1 aryl sulfotransferase

2.8.2.2 alcohol sulfotransferase

2.8.2.3 amine sulfotransferase

2.8.2.4 estrone sulfotransferase

2.8.2.5 chondroitin 4-sulfotransferase

2.8.2.6 choline sulfotransferase

2.8.2.7 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase

2.8.2.8 [heparan sulfate]-glucosamine N-sulfotransferase

2.8.2.9 tyrosine-ester sulfotransferase

2.8.2.10 Renilla-luciferin sulfotransferase

2.8.2.11 galactosylceramide sulfotransferase

2.8.2.12 created 1972, deleted 2001

2.8.2.13 psychosine sulfotransferase

2.8.2.14 bile-salt sulfotransferase

2.8.2.15 steroid sulfotransferase

2.8.2.16 thiol sulfotransferase

2.8.2.17 chondroitin 6-sulfotransferase

2.8.2.18 cortisol sulfotransferase

2.8.2.19 triglucosylalkylacylglycerol sulfotransferase

2.8.2.20 protein-tyrosine sulfotransferase

2.8.2.21 keratan sulfotransferase

2.8.2.22 aryl-sulfate sulfotransferase

2.8.2.23 [heparan sulfate]-glucosamine 3-sulfotransferase 1

2.8.2.24 aromatic desulfoglucosinolate sulfotransferase

2.8.2.25 flavonol 3-sulfotransferase

2.8.2.26 quercetin-3-sulfate 3′-sulfotransferase

2.8.2.27 quercetin-3-sulfate 4′-sulfotransferase

2.8.2.28 quercetin-3,3′-bissulfate 7-sulfotransferase

2.8.2.29 [heparan sulfate]-glucosamine 3-sulfotransferase 2

2.8.2.30 [heparan sulfate]-glucosamine 3-sulfotransferase 3

2.8.2.31 petromyzonol sulfotransferase

2.8.2.32 scymnol sulfotransferase

2.8.2.33 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

2.8.2.34 glycochenodeoxycholate sulfotransferase

2.8.2.35 dermatan 4-sulfotransferase

2.8.2.36 desulfo-A47934 sulfotransferase

2.8.2.37 trehalose 2-sulfotransferase

2.8.2.38 aliphatic desulfoglucosinolate sulfotransferase

2.8.2.39 hydroxyjasmonate sulfotransferase

2.8.2.40 ω-hydroxy-β-dihydromenaquinone-9 sulfotransferase

2.8.3 CoA-transferases

2.8.3.1 propionate CoA-transferase

2.8.3.2 oxalate CoA-transferase

2.8.3.3 malonate CoA-transferase

2.8.3.4 created 1961, deleted 1964

2.8.3.5 3-oxoacid CoA-transferase

2.8.3.6 3-oxoadipate CoA-transferase

2.8.3.7 succinate—citramalate CoA-transferase

2.8.3.8 acetate CoA-transferase

2.8.3.9 butyrate—acetoacetate CoA-transferase

2.8.3.10 citrate CoA-transferase

2.8.3.11 citramalate CoA-transferase

2.8.3.12 glutaconate CoA-transferase

2.8.3.13 succinate—hydroxymethylglutarate CoA-transferase

2.8.3.14 5-hydroxypentanoate CoA-transferase

2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

2.8.3.16 formyl-CoA transferase

2.8.3.17 3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase

2.8.3.18 succinyl-CoA:acetate CoA-transferase

2.8.3.19 CoA:oxalate CoA-transferase

2.8.3.20 succinyl-CoA—D-citramalate CoA-transferase

2.8.3.21 L-carnitine CoA-transferase

2.8.3.22 succinyl-CoA—L-malate CoA-transferase

2.8.3.23 caffeate CoA-transferase

2.8.3.24 (R)-2-hydroxy-4-methylpentanoate CoA-transferase

2.8.3.25 bile acid CoA-transferase

2.8.3.26 succinyl-CoA:mesaconate CoA transferase

2.8.3.27 propanoyl-CoA:succinate CoA transferase

2.8.3.28 phenylsuccinyl-CoA transferase

2.8.4 Transferring alkylthio groups

2.8.5 Thiosulfotransferases

2.9 Transferring selenium-containing groups

2.10 Transferring molybdenum- or tungsten-containing groups

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Release 2023.1 (January 2023)