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EC 2.8.4.2 Details

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EC number

2.8.4.2

Accepted name

arsenate-mycothiol transferase

Reaction

arsenate + mycothiol = arseno-mycothiol + H₂O

Other name(s)

ArsC1, ArsC2, mycothiol:arsenate transferase

Systematic name

mycothiol:arsenate S-arsenotransferase

Comment

Reduction of arsenate is part of a defence mechanism of the cell against toxic arsenate. The product arseno-mycothiol is reduced by EC 1.20.4.3 (mycoredoxin) to arsenite and mycothiol-mycoredoxin disulfide. Finally, a second mycothiol recycles mycoredoxin and forms mycothione.

History

created 2010

EC Tree

1 Oxidoreductases

2 Transferases

2.1 Transferring one-carbon groups

2.2 Transferring aldehyde or ketonic groups

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.2 Aminoacyltransferases

2.3.3 Acyl groups converted into alkyl groups on transfer

2.4 Glycosyltransferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.6 Transferring nitrogenous groups

2.7 Transferring phosphorus-containing groups

2.8 Transferring sulfur-containing groups

2.8.1 Sulfurtransferases

2.8.2 Sulfotransferases

2.8.3 CoA-transferases

2.8.4 Transferring alkylthio groups

2.8.4.1 coenzyme-B sulfoethylthiotransferase

2.8.4.2 arsenate-mycothiol transferase

2.8.4.3 tRNA-2-methylthio-N⁶-dimethylallyladenosine synthase

2.8.4.4 [ribosomal protein S12] (aspartate⁸⁹-C³)-methylthiotransferase

2.8.4.5 tRNA (N⁶-L-threonylcarbamoyladenosine³⁷-C²)-methylthiotransferase

2.8.4.6 S-methyl-1-thioxylulose 5-phosphate methylthiotransferase

2.8.5 Thiosulfotransferases

2.9 Transferring selenium-containing groups

2.9.1 Selenotransferases

2.10 Transferring molybdenum- or tungsten-containing groups

2.10.1 Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors